Search Business Hotels in Santa Cruz Island

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz Island Business Hotels

Tonight
5 Dec - 6 Dec
Tomorrow
6 Dec - 7 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Santa Cruz Island Business Hotels

Exterior
Capitan Max B&B

Capitan Max B&B

3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (194)
"Max is the owner, he is a great host!"
United States
Wenhaw
Capitan Max B&B
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas, pool loungers
Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton

4.5 star property
Santa Rosa
9.2 out of 10, Wonderful, (52)
"The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again."
United States
Laureen
The price is ₹22,060
₹24,266 total
20 Dec - 21 Dec
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Exterior detail
Suymar Ecolodge Galapagos

Suymar Ecolodge Galapagos

3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (14)
"Incredible stay - would highly recommend this to anyone looking to stay a little out of the port area but not too far"
United States
Porcia
Suymar Ecolodge Galapagos
Sun deck
Hotel Solymar

Hotel Solymar

3.0 star property
Puerto Ayora
7.8 out of 10, Good, (59)
"Great place to stay. "
United States
VISHAL
Hotel Solymar
Courtyard
Hotel Deja Vu

Hotel Deja Vu

3.0 star property
Puerto Ayora
7.6 out of 10, Good, (28)
"excellent service, the staff is very friendly 🙂 good location, you can walk to the main street"
Mexico
Danaee
Hotel Deja Vu
Family Room, 2 Bedrooms | 1 bedroom, Egyptian cotton sheets, premium bedding, minibar
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (173)
"Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel. "
United States
Susanna
Hotel el descanso del Guia
Free daily buffet breakfast
Ikala Galapagos Hotel

Ikala Galapagos Hotel

4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (126)
"Nice clean hotel"
United States
Marco
The price is ₹19,772
₹21,750 total
22 Dec - 23 Dec
Ikala Galapagos Hotel
Front of property
Lava House Hostal

Lava House Hostal

3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (51)
"Friendly, quiet, excellent service and accommodations. "
United States
Diane
Lava House Hostal
Front of property
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (121)
"We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. "
United States
Doreen
The price is ₹25,022
₹27,525 total
7 Dec - 8 Dec
Blu Galapagos Sustainable Waterfront Lodge
Terrace/patio
Palo Santo Galapagos Hotel

Palo Santo Galapagos Hotel

3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (17)
"This is a really nice property, but for me a pool is very important when I stay at a resort. The pool water was cloudy and not very appealing/inviting. The area around the pool itself was great."
United States
Wesley
The price is ₹19,435
₹21,378 total
4 Jan - 5 Jan 2026
Palo Santo Galapagos Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Cruz Island Hotel Reviews

Hotel el descanso del Guia

Hotel el descanso del Guia

10/10 Excellent
"What really stood out was the exceptional customer service. Everyone was friendly, professional, and always willing to help with anything I needed. The location was perfect, and the atmosphere made my stay Monica"
Monica Patricia 5-night trip
Posted 2 weeks ago
Hotel el descanso del Guia

Explore a world of travel with Expedia