The Best Hotels in Downtown Santa Ana, Santa Ana - 2026 Updated Prices

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Our top choices for Downtown Santa Ana hotels

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring multiple balconies and a prominent entrance.

1. Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Lyon Street, 2.1 km from Downtown Santa Ana

Vishal

₹12,544 total

includes taxes & fees

10 Dec - 11 Dec

A hotel lobby with seating areas, a reception desk, and a large window offering a view of the outside.

2. Best Western Plus Orange County Airport North

4.3 km from Downtown Santa Ana

du

₹11,556 total

includes taxes & fees

16 Nov - 17 Nov

A stone fire pit surrounded by palm trees and chairs in an outdoor seating area.

3. MainStay Suites John Wayne Airport by Choice Hotels

4.3 km from Downtown Santa Ana

Dariana

₹9,397 total

includes taxes & fees

1 Dec - 2 Dec

A hotel with a covered entrance, palm trees, and a well-lit facade.

4. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

4.5 km from Downtown Santa Ana

Asghar

₹11,162 total

includes taxes & fees

25 Nov - 26 Nov

A living room with a fireplace, wooden coffee table, and comfortable seating.

5. Ayres Hotel Orange

5 km from Downtown Santa Ana

Vicente

₹13,881 total

includes taxes & fees

24 Nov - 25 Nov

A multi-story hotel with outdoor seating areas featuring wicker furniture and a central fire feature.

6. La Quinta Inn & Suites by Wyndham Orange County Airport

4.4 km from Downtown Santa Ana

Travis Lennox

₹9,619 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with two beds, a bathroom, and a view of a bridge.

7. Orange Grove Inn

5.5 km from Downtown Santa Ana

Kristina

₹7,824 total

includes taxes & fees

11 Dec - 12 Dec

An outdoor seating area with fire pits, modern furniture, and a view of the sky.

8. Hotel Fera Anaheim, a DoubleTree by Hilton

5 km from Downtown Santa Ana

Wendy

₹11,878 total

includes taxes & fees

29 Nov - 30 Nov

A modern lounge area with seating arrangements, a staircase, and a view of the upper floors.

9. Embassy Suites by Hilton Irvine Orange County Airport

7.3 km from Downtown Santa Ana

Erika

₹14,352 total

includes taxes & fees

11 Dec - 12 Dec

A modern living room with a staircase, a sofa, and a small dining area.

10. Lemon Heights Inn

5.4 km from Downtown Santa Ana

Akeem

₹9,360 total

includes taxes & fees

10 Dec - 11 Dec

A hotel with a dome and arched windows, a covered entrance, and palm trees.

11. Hotel Marguerite Anaheim/Garden Grove, Trademark Collection by Wyndham

4.7 km from Downtown Santa Ana

Renee

₹12,314 total

includes taxes & fees

15 Nov - 16 Nov

A modern restaurant with a sunset mural, contemporary furniture, and a view of the ocean.

12. Hyatt Regency Irvine

8.2 km from Downtown Santa Ana

Karen

₹23,181 total

includes taxes & fees

28 Nov - 29 Nov

A hotel lobby with multiple seating areas, palm trees, and a large glass facade.

13. Hyatt Regency Orange County

6.4 km from Downtown Santa Ana

Jacklyn

₹15,575 total

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with a fireplace, seating area, and a large wooden cabinet.

14. Ayres Hotel Anaheim

6.6 km from Downtown Santa Ana

Yun

₹13,183 total

includes taxes & fees

29 Nov - 30 Nov

A bar with hanging plants, a mural, and shelves of bottles.

15. ALO Hotel by Ayres, Orange

5.1 km from Downtown Santa Ana

Alfonso

₹11,924 total

includes taxes & fees

29 Nov - 30 Nov

A modern interior with a large glass wall, a dining area with a long table and chairs, a sofa set, and a staircase.

16. Sonesta Irvine John Wayne Airport

7.6 km from Downtown Santa Ana

Rosalinda

₹15,216 total

includes taxes & fees

25 Nov - 26 Nov

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and artwork on the walls.

17. Delta Hotels by Marriott Anaheim Garden Grove

6.2 km from Downtown Santa Ana

Martha

₹14,537 total

includes taxes & fees

9 Dec - 10 Dec

An indoor swimming pool with a high ceiling, visible structural beams, and a central water slide.

18. Great Wolf Lodge Anaheim, CA

5.6 km from Downtown Santa Ana

Rosa Ann

₹19,122 total

includes taxes & fees

29 Nov - 30 Nov

A multi-level hotel lobby with a central pool, seating areas, and a modern architectural design.

19. Embassy Suites by Hilton Anaheim South

6.6 km from Downtown Santa Ana

Joanna

₹14,878 total

includes taxes & fees

29 Nov - 30 Nov

A swimming pool area with two pools, a blue chair, and a building with multiple windows in the background.

20. Wyndham Anaheim

7.5 km from Downtown Santa Ana

Richard

₹18,590 total

includes taxes & fees

29 Nov - 30 Nov

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Compare popular hotels in Downtown Santa Ana

Property	Property class	Guest rating
Holiday Inn Express & Suites Santa Ana - Orange County by IHG	2.5 star property	8.8 Excellent 1,243 reviews	View
Best Western Plus Orange County Airport North	2.5 star property	8.6 Excellent 1,958 reviews	View
Ayres Hotel Orange	3.5 star property	9.6 Exceptional 3,196 reviews	View
Holiday Inn Santa Ana-Orange Co. Arpt by IHG	3.0 star property	8.8 Excellent 1,632 reviews	View
Hyatt Regency Irvine	4.0 star property	9.4 Exceptional 1,246 reviews	View

Hotels recommended for families in Downtown Santa Ana

Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Lyon Street

₹12,544 total

includes taxes & fees

10 Dec - 11 Dec

Where to stay in Downtown Santa Ana

Find the best Downtown Santa Ana areas for the activities you enjoy most.

A sprawling urban area with a prominent highway, surrounded by residential neighborhoods and distant mountains.

North Tustin

While North Tustin isn't home to many top sights, The Market Place and Irvine Regional Park are some notable places to visit nearby.

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An aerial view of a city with a river, bridges, and a highway.

Riverview West

While Riverview West may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like David L. Baker Memorial Golf Center and Mile Square Regional Park.

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A large dinosaur skeleton exhibit with a prominent skull in the foreground and a massive tail structure in the background.

Park Santiago

While visiting Park Santiago, you might make a stop by sights like Discovery Science Center and Santiago Park.

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A blue and yellow parrot with a black beak and white face, perched on a branch.

Lyon Street

While Lyon Street isn't home to many top sights, Santa Ana Zoo and Cabrillo Tennis Center are some notable places to visit nearby.

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A hockey player in a black and orange uniform with a helmet and gloves.

Henninger Park

If you're looking for some top things to see and do in Henninger Park and surrounding area, you can visit Old Orange County Courthouse and Yost Theater.

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Top Downtown Santa Ana Hotel Reviews

Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Lyon Street

10/10 Excellent

Thomas

ALO Hotel by Ayres, Orange

Anaheim Resort

10/10 Excellent

As a solo traveller, I had a very comfortable and seamless stay. The room was spotlessly clean and spacious, providing plenty of room to relax. The staff were incredibly helpful and welcoming from check-in to checkout. The complimentary breakfast was standard but good, though it could definitely do with a few more choices to change things up. Overall, it's a safe, clean, and reliable option for anyone travelling on their own.

Maria Nerissa

MainStay Suites John Wayne Airport by Choice Hotels

Santa Ana

10/10 Excellent

Dorota Anna

Hotel Fera Anaheim, a DoubleTree by Hilton

Anaheim Resort

10/10 Excellent

ahmer

Ayres Hotel Anaheim

Southeast Anaheim

10/10 Excellent

James

A spacious lobby with a fireplace, multiple seating areas, and a chandelier.

Ayres Hotel Fountain Valley - Huntington Beach

Downtown Village

10/10 Excellent

Quoc Phong

Sonesta Irvine John Wayne Airport

Irvine Business Complex

10/10 Excellent

Colin

Wyndham Anaheim

Anaheim Resort

10/10 Excellent

Kavita

La Quinta Inn & Suites by Wyndham Orange County Airport

Santa Ana

10/10 Excellent

Claire

Embassy Suites by Hilton Anaheim South

Anaheim Resort

10/10 Excellent

Lynsey

A spacious living room with a fireplace, comfortable seating, and a high ceiling.

Ayres Hotel Costa Mesa/Newport Beach

Santa Ana

10/10 Excellent

Robert

Frequently Asked Questions

What is Downtown Santa Ana like?

Guests are sure to enjoy their time checking out all that Santa Ana's Downtown Santa Ana neighbourhood has to offer. Are you looking for Downtown Santa Ana travel tips? Make sure that you visit Santora Arts Building and 4th Street Market while you're in the neighbourhood.

How many hotels will I be able to find in the Downtown Santa Ana area?

When you want to put your feet up after a day of exploring the sights in Santa Ana, you can choose from 10 Expedia hotels and other accommodation options in Downtown Santa Ana.

If I need to cancel my hotel reservation in Downtown Santa Ana, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the best options available in Downtown Santa Ana.

What are the top things to see and do in Downtown Santa Ana?

A few attractions you might want to check out while you're in Downtown Santa Ana are Santora Arts Building and 4th Street Market. Old Orange County Courthouse and Dr. Willella Howe-Waffle House and Medical Museum are also worth a visit when you're out sightseeing in Santa Ana.

Search Hotels in Downtown Santa Ana, Santa Ana

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Treat yourself

Be picky

Check prices for these dates

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Property class

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Our top choices for Downtown Santa Ana hotels

1. Holiday Inn Express & Suites Santa Ana - Orange County by IHG

2. Best Western Plus Orange County Airport North

3. MainStay Suites John Wayne Airport by Choice Hotels

4. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

5. Ayres Hotel Orange

6. La Quinta Inn & Suites by Wyndham Orange County Airport

7. Orange Grove Inn

8. Hotel Fera Anaheim, a DoubleTree by Hilton

9. Embassy Suites by Hilton Irvine Orange County Airport

10. Lemon Heights Inn

11. Hotel Marguerite Anaheim/Garden Grove, Trademark Collection by Wyndham

12. Hyatt Regency Irvine

13. Hyatt Regency Orange County

14. Ayres Hotel Anaheim

15. ALO Hotel by Ayres, Orange

16. Sonesta Irvine John Wayne Airport

17. Delta Hotels by Marriott Anaheim Garden Grove

18. Great Wolf Lodge Anaheim, CA

19. Embassy Suites by Hilton Anaheim South

20. Wyndham Anaheim

Compare popular hotels in Downtown Santa Ana

Hotels recommended for families in Downtown Santa Ana

Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Where to stay in Downtown Santa Ana

North Tustin

Riverview West

Park Santiago

Lyon Street

Henninger Park

Top Downtown Santa Ana Hotel Reviews

Holiday Inn Express & Suites Santa Ana - Orange County by IHG

10/10 Excellent

Frequently Asked Questions

What is Downtown Santa Ana like?

How many hotels will I be able to find in the Downtown Santa Ana area?

If I need to cancel my hotel reservation in Downtown Santa Ana, will I receive a refund?

What are the top things to see and do in Downtown Santa Ana?