Samos Prefecture Trip

Book a Hotel + Flight or Car together to unlock savings

Photo by Erica Previtali

  • Plan, book, travel with confidence

  • Better together

    Save up to ₹43,962 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Samos Prefecture

Casa Cook Samos

Casa Cook Samos

5 out of 5
Potokaki, Pythagorion Samos
9.4/10 Exceptional! (95 reviews)
Clean and modernly decorated rooms with all the facilities

Reviewed on 31 Oct 2025

Get rates
Casa Cook Samos
Samos Bay Hotel

Samos Bay Hotel

3 out of 5
Main Street Samos Samos Island
8/10 Very Good! (73 reviews)
Room was very tiny - though the view was beautiful

Reviewed on 9 Sept 2025

Get rates
Samos Bay Hotel
Doryssa Lithos Hotel

Doryssa Lithos Hotel

2 out of 5
Pythagorion Samos
9.6/10 Exceptional! (25 reviews)
This property was ideally located above the port of pythagorion. Service was super friendly, staff charming with wonderful breakfasts by the pool included. They work hard to keep the property spotless and we'll maintained. Highly recommend.

Reviewed on 13 Oct 2025

Get rates
Doryssa Lithos Hotel
See all 349 properties in Samos Prefecture
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Ruins of Ancient City, Archaeological Museum, Pythagoreion, UNESCO World Heritage Site, Pythagoreio, Samos Island, North Aegean

Samos Pythagorion Archaeological Museum

You can browse the exhibits at Samos Pythagorion Archaeological Museum, a museum with a storied past, during your holiday in Pythagorio. Wander the beaches and seaside in the area.

Samos Pythagorion Archaeological Museum

Gagou Beach

Why not spend a care-free afternoon at Gagou Beach during your travels in Kalami? While you're in the area, stroll along the waterfront.

Gagou Beach

Megalo Seitani Beach

Why not spend a care-free afternoon at Megalo Seitani Beach during your travels in Karlovassi? Wander the waterfront or discover the area's mountain views.

Megalo Seitani Beach

Frequently asked questions

Can I cancel my flight booking to Samos Prefecture due to COVID-19?
Many airlines now provide more flexibility due to COVID-19. Our handy Customer Service Portal will help find an answer to most queries about which policies apply to your flight. It's also wise to check the terms and conditions of your preferred carrier — preferably before purchasing your tickets!
What's the best way to find cheap flights to Samos Prefecture that have flexible change policies?
At Expedia, we've been channeling our inner yoga master to get you the most flexible fares around. Just mark the "No change fee" box under the filter subheading "Flexible change policies" to find your dream flight to Samos Prefecture.
What are some of the general tips for travellers to Samos Prefecture during the COVID-19 outbreak?
COVID-19 has changed how the world works in ways big and small, including our approach to travel. These tips will help you understand the new challenges and get you ready for your trip to Samos Prefecture:
  • Look into if any restrictions apply to both your origin and destination. It may not be possible to travel depending on local circumstances, so make sure you check before you lock in your flight.
  • When you pass through airport screening, keep your face mask on. You will be required to lower it briefly for ID purposes. Passengers who refuse to wear a mask may be fined and denied entry.
  • To avoid cross-contamination, position your boarding pass on the scanner yourself and then hold it up for inspection. Do not hand your pass directly to a TSA employee.
  • TSA is now allowing passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on bags. This will need to be removed from your bag for screening.
  • To minimize handling during the screening process, place personal items such as your loose change and phone into your carry-on rather than into the bins.
  • If you're taking food on board, place it in a clear plastic bag and then into a screening bin. This lessens the likelihood that a TSA agent will need to handle your carry-on bag or food container for inspection.

Which airlines fly to Samos Prefecture?
Arrange your ticket with Olympic Air and then start organising your Samos Prefecture travel agenda. This top carrier provides 95 flights every month to Samos Intl. Airport (SMI), a major gateway.
How can I find cheap tickets to Samos Prefecture?
Book well ahead of time, consider nearby airports, use miles or points — there are plenty of ways! Another one is to take advantage of Expedia's "flexible dates" function. Search for your Samos Prefecture flight, then compare the cheapest prices for nearby dates. In the last seven days, the lowest price for a flight to Samos Prefecture was .
How much is a flight to Samos Prefecture?
There were plenty of cheap fares up for grabs in the last seven days, with the cost of a return flight to Samos Prefecture varying between and . Many lucky travellers scored one-way seats from () for just .
What are the most popular airports to fly into in Samos Prefecture?
Samos Intl. Airport (SMI) is the main airport for those travelling to and from Samos Prefecture. Around 260 flights a month touch down at this airport.
When is the cheapest time to fly to Samos Prefecture?
Depart for Samos Prefecture early in the week and you'll usually be rewarded with lower fares. Tuesday is known for being the cheapest day to fly out, followed closely by Monday. If you'd like to avoid the priciest flights, stay away from Saturdays.
How much is a plane ticket to Samos Prefecture?
In the last seven days, plane tickets cost between and . Swipe through our awesome deals to Samos Prefecture, pick your favourite and then start packing your suitcase.
Which airlines with flights to Samos Prefecture employ COVID-19 cleanliness policies?
While flying in a pandemic has its challenges, airlines have gone above and beyond to protect the well-being of passengers and cabin crew. These are a few carriers that have introduced changes:
  • Olympic Air - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Sky Express - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Condor - this airline is known for providing passenger masks and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.