A coastal town with a pier, boats, and a hillside with buildings.

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Check availability on Pythagorio Spa Hotels

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Our top choices for Pythagorio hotels with a spa

A pool area with steps leading into the water, a bench, and a stone wall.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.
A room with a view of the sea through sheer curtains, a wooden bed, and a balcony with a chair and a table.
A bar area with a wooden counter and stools.

1. Casa Cook Samos

Casa Cook Samos
Samos
  • Immerse in a beachfront boutique escape with 4 specialised treatment rooms and daily aromatherapy spa services for complete renewal.
₹21,878
₹25,561 total
includes taxes & fees
28 Oct - 29 Oct
Casa Cook Samos
A poolside area with lounge chairs and an umbrella, overlooking a clear blue sea and distant mountains.
A balcony with a view of a coastal area, including a beach and a mountainous backdrop.
A terrace with a view of the sea and a mountainous landscape.
A coastal landscape with trees framing a beach and clear blue sea.

2. Armonia Bay Hotel

Armonia Bay Hotel
Samos
  • Mediterranean retreat offers rejuvenating seaside escapes with massages, infinity pools, and garden serenity.
₹12,524
₹14,783 total
includes taxes & fees
25 Oct - 26 Oct
Armonia Bay Hotel
A spacious lobby with a marble floor, white sofas, and potted plants.
A pool area with a wooden pergola structure, a clear night sky, and a mountain backdrop.
An outdoor seating area with modern furniture and a stone wall.
An outdoor dining area with wicker furniture, a bar with shelves of bottles, and a view of trees and mountains in the background.

3. Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa
Samos
  • Serene beachfront escape with two outdoor pools and an on-site spa offering rejuvenating treatments in scenic surroundings.
₹8,203
₹10,050 total
includes taxes & fees
27 Oct - 28 Oct
Samian Mare Hotel Suites & Spa
A modern outdoor terrace with a pool, seating, and a view of a coastal town.
A modern bathroom with a large window, a shower, a sink with a mirror, and a towel rack.
A room with a view of a coastal landscape, a sofa, a table with a bowl, and a chair.
Room

4. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
₹14,853
₹17,866 total
includes taxes & fees
25 Oct - 26 Oct
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
A reception area with two curved reception desks, a laptop, potted plants, and a wooden cabinet in the background.
A restaurant with a view of the ocean, wooden tables and chairs, and a bar area with shelves of bottles and glasses.
A hotel room with a large bed, a sofa, a dining area, and a view of the sea.
A wooden deck with lounge chairs and a thatched umbrella.

5. Erato by Samian Mare

Erato by Samian Mare
Samos
  • Discover tranquil waterfront wellness at this eco-certified spa retreat, featuring couples' treatment rooms and traditional Turkish baths.
₹10,421
₹12,479 total
includes taxes & fees
30 Oct - 31 Oct
Erato by Samian Mare
A circular seating area with mosaic tile walls and a central pillar.
A buffet setup with various food items and serving utensils.
A reception area with a wooden reception desk, a clock, and a reception sign.
An outdoor patio area with tables and chairs, a pool, and umbrellas.

6. Aegeon

Aegeon
Samos
  • Unwind at this island hotel with tranquil spa treatments, including massage services in 2 treatment rooms and a relaxing Turkish bath.
₹6,019
₹7,126 total
includes taxes & fees
26 Oct - 27 Oct
Aegeon
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Choose what matters most at spa hotels in Pythagorio

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Pythagorio Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Pythagorio?
Treat yourself to some pampering and book a hotel with a spa. Discover the historical sites and museums in Pythagorio—your cultural tour starts here. Make sure you pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness centre, a hair salon, a beach bar and a restaurant. Treat yourself to a facial, body scrub or Swedish massage at the on-site spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort.
How many spa hotels are there in Pythagorio?
Among Expedia's 74 accommodation options in Pythagorio, there are 5 spa hotels.
What's there to see and do in Pythagorio?
Take in the sights and attractions that Pythagorio offers with a visit to Samos Pythagorion Archaeological Museum, Pythagoreion and Glicorisa Beach. If you have extra time while you're in the area, you might want to stop by Tunnel of Eupalinos and Potakaki beach.
What is a Pythagorio spa hotel?
Spa hotels in Pythagorio feature on-site spas and offer services including couples massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.