A coastal town with a pier, boats, and a hillside with buildings.

Search Luxury Hotels in Pythagorio

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Check availability on Pythagorio Luxury Hotels

Tonight
8 Sept - 9 Sept
Tomorrow
9 Sept - 10 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Our top choices for Pythagorio luxury hotels

1. Casa Cook Samos

Casa Cook Samos
Samos
  • Beachfront luxury meets spa indulgence at Casa Cook Samos, where Mediterranean elegance awaits.
₹19,634
₹23,156 total
includes taxes & fees
1 Oct - 2 Oct
Casa Cook Samos

2. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
  • Relish beachfront luxury at this Samos seaside resort where warm staff, 2 outdoor pools, and a private beach create an indulgent escape.
₹18,082
₹21,456 total
includes taxes & fees
9 Oct - 10 Oct
Doryssa Seaside Resort

3. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Private beachfront luxury meets seaside serenity at this adults-only Samos resort offering spa indulgences and ocean-view dining.
₹15,757
₹18,909 total
includes taxes & fees
9 Oct - 10 Oct
Proteas Blu Resort - Adults Only

4. Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
₹10,575
₹12,683 total
includes taxes & fees
9 Oct - 10 Oct
Hydrele Beach Hotel

5. Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
₹10,651
₹12,766 total
includes taxes & fees
5 Oct - 6 Oct
Doryssa Theorem Hotel

6. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
₹13,071
₹15,418 total
includes taxes & fees
9 Oct - 10 Oct
Doryssa Boutique Hotel

7. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
₹27,375
₹31,636 total
includes taxes & fees
8 Oct - 9 Oct
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

8. Erato by Samian Mare

Erato by Samian Mare
Samos
₹12,927
₹15,259 total
includes taxes & fees
28 Sept - 29 Sept
Erato by Samian Mare

9. Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa
Samos
₹10,729
₹12,852 total
includes taxes & fees
13 Sept - 14 Sept
Samian Mare Hotel Suites & Spa

10. Arion Hotel

Arion Hotel
Samos
Arion Hotel
View all properties

Top Pythagorio Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

8/10 Good
"Very good, friendly place"
Zafer 3-night trip
Posted 10 days ago
Doryssa Seaside Resort
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

8/10 Good
"Inner architecture is not good, rooms are good and clean, staff are really nice and helpful. I bought sea view room but it was not that much sea view it was more like concrete view, Beach and pool side are quite nice Breakfast was very good"
ercan 1-night trip
Posted 1 month ago
Proteas Blu Resort - Adults Only

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Pythagorio?
During your visit, you might want to enjoy the port which Pythagorio is known for.
What's the best luxury hotel in Pythagorio?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your trip.
When can I expect good weather in Pythagorio?
Planning for the weather is an important factor for making your trip to Pythagorio a success, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 13°C. Average annual precipitation for Pythagorio is 837 mm.
What's there to see and do in Pythagorio?
Experience Pythagorio with a stop at Samos Pythagorion Archaeological Museum, Pythagoreion and Glicorisa Beach. If you have spare time during your trip, you might want to make a stop at Folklore Museum of the Nikolaos Dimitriou Foundation of Samos and Tunnel of Eupalinos.