𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 O Brien (2026)

A calm river with clear water, surrounded by dense trees and rocky banks.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in O Brien

Pet friendly

Apartment

Pool

Family friendly

Condo

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for O Brien hotels

A La Quinta hotel with a modern facade, multiple windows, and a well-lit entrance.

A hotel room with a large bed, a sofa, a desk, and a wall with a geometric pattern.

A modern restaurant with a long counter, multiple seating options including red and yellow chairs, and a large window providing a view.

A modern kitchen area with a coffee station, including a coffee machine, cups, and a toaster.

1. La Quinta Inn & Suite by Wyndham Lake City

Lake City

Jack

₹8,971

₹10,092 total

includes taxes & fees

25 Oct - 26 Oct

A spacious living area with a grey sofa, a coffee table, and a TV stand.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

A modern kitchen with light wood cabinets, granite countertops, and stainless steel appliances. There are signs on the wall advertising different coffee brands.

A hotel entrance with a covered walkway, palm trees, and a clear sky.

2. Best Western Plus Lake City

Lake City

Melissa

₹7,568

₹8,514 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a gray sofa, a bed with white linens, a desk with a chair, and a window with blinds.

A modern hotel lobby with a central island table, seating area with chairs, a fireplace, and a bar area.

A modern hotel lobby with a fireplace, seating areas, and a bar.

A modern living room with a sectional sofa, a round coffee table, a hanging chair, and a flat-screen TV on a glass stand.

3. Comfort Suites Lake City

Lake City

Brooke

₹9,692

₹10,903 total

includes taxes & fees

22 Nov - 23 Nov

4. Hampton Inn & Suites Lake City

Lake City

James

₹9,908

₹11,146 total

includes taxes & fees

25 Oct - 26 Oct

A modern interior with two red chairs and a small table, large windows, and hanging pendant lights.

A modern hotel lobby with a central counter displaying snacks and beverages, two digital screens above the counter, and a seating area with a view of the lobby.

A modern hotel with a flat roof, multiple windows, and a covered entrance.

A self-service beverage station with a variety of drinks, snacks, and a refrigerated section.

5. Tru by Hilton Lake City

Lake City

Carlos

₹9,447

₹10,628 total

includes taxes & fees

19 Nov - 20 Nov

An indoor swimming pool with clear water, surrounded by glass doors and windows, and a wooden deck area.

An outdoor patio area with a sectional sofa, chairs, a coffee table, and a fire pit.

A modern lounge area with a fireplace, comfortable seating, a dining table, and a large window offering a view.

A modern dining area with multiple tables and chairs, a kitchen in the background, and a 'Hello Fall' sign on the wall.

6. Fairfield Inn & Suites Lake City

Lake City

Anthony

₹8,885

₹9,995 total

includes taxes & fees

29 Oct - 30 Oct

An outdoor patio with a stone fire pit, grey cushioned seating, and wicker ottomans.

A modern hotel with a two-story structure, a covered outdoor seating area, and a parking lot with marked spaces.

A modern kitchen with stainless steel appliances, a dishwasher, and a built-in oven.

A modern hotel room with a bed, a desk with a computer, a TV, and a lamp.

7. Home2 Suites by Hilton Lake City

Lake City

Laurie

₹11,212

₹12,613 total

includes taxes & fees

25 Oct - 26 Oct

A picnic table with a potted plant, located in a grassy area with a tree and a road in the background.

A hotel lobby with a view of the street, a reception desk, and a large map on the wall.

A hotel room with two beds, a nightstand with a phone and remote, and a patterned curtain.

A living room with a black leather sofa, a wooden coffee table with a plant, and framed pictures on the wall.

8. Americas Best Value Inn Lake City

Lake City

Sara

₹6,717

₹7,558 total

includes taxes & fees

25 Oct - 26 Oct

A multi-story hotel with a modern design, featuring a prominent entrance and a parking area.

A modern restaurant with round tables and yellow chairs, a bar area with a TV, and a menu display.

A reception area with two wooden reception desks, a wall-mounted decorative piece, and a refrigerator stocked with beverages.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

9. Courtyard By Marriott Lake City

Lake City

Angel

₹10,968

₹12,339 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with wicker chairs, a round table, and a fire pit.

A modern interior with a sofa, round tables, and chairs, a TV mounted on the wall, and a patterned wall.

A modern interior with a dark wood desk, a blue chair, a sofa, and a patterned rug.

A hotel room with a bed, a sofa, a small table, a wardrobe, and a kitchenette.

10. TownePlace Suites by Marriott Lake City

Lake City

John

₹12,186

₹13,710 total

includes taxes & fees

22 Nov - 23 Nov

A reception area with a counter, seating, and a fireplace.

A modern restaurant with a central counter, red chairs, and a blue and white color scheme.

A hotel room with a bed, a desk with a coffee maker, a chair, and a lamp.

A hotel with a covered entrance, a sign indicating it is a Holiday Inn Express, and a well-maintained lawn area.

11. Holiday Inn Express & Suites Live Oak by IHG

Live Oak

Tammy

₹10,392

₹11,431 total

includes taxes & fees

15 Nov - 16 Nov

A hotel lobby with multiple seating areas, including round tables and booths, and a high ceiling with recessed lighting.

A hotel room with a beige sofa, a small table with a book, a TV on a wooden cabinet, and a window with blinds.

A multi-story hotel with a prominent 'Holiday Inn' sign, balconies, and a palm tree.

A gym with treadmills, weight machines, and dumbbells.

12. Holiday Inn & Suites Lake City by IHG

Lake City

C.jeffery

₹8,975

₹10,096 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with a high ceiling, a large window, a dining area with green chairs, and a black door leading outside.

A hotel dining area with tables and chairs, a reception desk, and a kitchen in the background.

A reception area with a counter, a coffee machine, and a potted plant.

A white building with multiple windows and a sign that reads 'Quality Inn.'

13. Quality Inn Lake City

Lake City

Dawn

₹7,147

₹8,040 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a large bed, a desk with a computer, a television, and a window with curtains.

A swimming pool with lounge chairs and umbrellas, surrounded by a brick building with balconies and palm trees.

An aerial view of a hotel with a swimming pool, parking lot, and surrounding greenery.

A restaurant with a yellow accent wall, white tiled floor, and black and blue chairs.

14. Super 8 by Wyndham Lake City

Lake City

Scott

₹5,862

₹6,595 total

includes taxes & fees

15 Nov - 16 Nov

A modern kitchen with a large window, a flat-screen TV, and a coffee machine.

A reception area with a tiled counter, a computer, a sign reading 'Quality,' and two decorative vases.

A hotel lobby with a dining area, a reception desk, and a view of the outside.

A hotel room with a bed, desk, chair, and sofa.

15. Quality Inn White Springs Suwanee

White Springs

Pennee

₹6,234

₹6,857 total

includes taxes & fees

15 Nov - 16 Nov

A reception area with a stone wall, a blue accent wall, a clock, and a window with a view of the parking lot.

A bathroom with a towel rack, a shower curtain, and a toilet.

Two doors, one blue and one green, with numbers 105 and 103 respectively, against a brick wall.

A bathroom with a bathtub, a shower, and a toilet.

16. Regal Inn

Lake City

Samuel

₹5,275

₹5,934 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a TV, a desk, and a painting of a sunset.

A kitchen with a black refrigerator and a microwave on a wooden shelf.

A reception area with a wooden counter, a clock, and a computer on a desk.

A hotel room with a large bed, a bedside table, a nightstand, a window, and a bathroom with a toilet and sink.

17. Days Inn by Wyndham Lake City I-75

Lake City

Nathan

₹6,953

₹7,822 total

includes taxes & fees

25 Oct - 26 Oct

A covered outdoor area with a paved walkway, benches, and potted plants.

A grassy area with a picnic table, a car parked in front of a building with a sloped roof, and trees with hanging moss.

A compact RV kitchen with wooden cabinets, a microwave, a stove, and a sink.

A compact kitchen with a blue refrigerator, a black coffee maker, a microwave, and a small black refrigerator.

18. Cindys Motel

Mayo

Diane

₹7,792

₹8,421 total

includes taxes & fees

22 Nov - 23 Nov

A hotel reception area with a reception desk, seating area, and a view of the parking lot.

A compact room with a flat-screen TV on a wooden cabinet, a microwave on a small black stand, a chair, and a mirror with a light above it.

A dining area with wooden chairs and tables, a coffee machine, and a counter with various items.

A hotel room with two beds, a bedside table with a lamp, a phone, and a window with curtains.

19. Econo Lodge Live Oak

Live Oak

Alexia

₹8,257

₹9,081 total

includes taxes & fees

2 Nov - 3 Nov

A spacious living area with a large chandelier, a sofa set, a coffee table, and a patterned floor.

A hotel with a classic facade, featuring a prominent sign reading "HOTEL BLANCHE".

A spacious lobby with a large chandelier, two sofas, a glass coffee table, and a patterned carpet.

A storefront with a glass door and a brick wall. The sign above the door reads "The Blanche."

20. The Blanche

Lake City

daniel

₹12,906

₹14,520 total

includes taxes & fees

27 Oct - 28 Oct

View all properties

Hotels recommended for families in O Brien

La Quinta Inn & Suite by Wyndham Lake City

Lake City

₹8,971

₹10,092 total

includes taxes & fees

25 Oct - 26 Oct

Comfort Suites Lake City

Lake City

₹9,692

₹10,903 total

includes taxes & fees

22 Nov - 23 Nov

Best Western Plus Lake City

Lake City

₹7,568

₹8,514 total

includes taxes & fees

15 Nov - 16 Nov

Tru by Hilton Lake City

Lake City

₹9,447

₹10,628 total

includes taxes & fees

19 Nov - 20 Nov

Americas Best Value Inn Lake City

Lake City

₹6,717

₹7,558 total

includes taxes & fees

25 Oct - 26 Oct

Hampton Inn & Suites Lake City

Lake City

₹9,908

₹11,146 total

includes taxes & fees

25 Oct - 26 Oct

Courtyard By Marriott Lake City

Lake City

₹10,968

₹12,339 total

includes taxes & fees

1 Nov - 2 Nov

Fairfield Inn & Suites Lake City

Lake City

₹8,885

₹9,995 total

includes taxes & fees

29 Oct - 30 Oct

Save an average of 15% on thousands of hotels when you're signed in

Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Hampton Inn & Suites Lake City

10/10 Excellent

"Nice new property and helpful staff. The outside pool was nice to be outside and relax. Lots of different seating. Rooms were nicely decorated and very comfortable."

Best Western Plus Lake City

10/10 Excellent

"Nice staff great rooms"

Hampton Inn & Suites Alachua I-75

10/10 Excellent

"Locationnperfect"

Quality Inn & Suites Live Oak I-10 Exit 283

8/10 Good

"Room was clean the TV didn't work would turn on but couldn't watch anything"

Fairfield Inn & Suites Lake City

10/10 Excellent

"Great place! Very clean. Awesome breakfast."