The Best Hotels in North Clayton, St. Louis - 2026 Updated Prices

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Our top choices for North Clayton hotels

A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

1. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

North Clayton

Kevin

₹14,054 total

includes taxes & fees

22 Nov - 23 Nov

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

2. Drury Plaza Hotel St. Louis Brentwood

3.1 km from North Clayton

Stacey Rochelle

₹13,660 total

includes taxes & fees

13 Dec - 14 Dec

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

3. SpringHill Suites St. Louis Brentwood

3.6 km from North Clayton

Aaron

₹13,911 total

includes taxes & fees

29 Nov - 30 Nov

An outdoor patio with a fire pit, seating, and a building in the background.

4. Courtyard by Marriott St. Louis Brentwood

3 km from North Clayton

Anna

₹13,582 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with two beds, a desk, a chair, and a television.

5. Clayton Plaza Hotel & Extended Stay

0.8 km from North Clayton

Martha

₹11,059 total

includes taxes & fees

13 Dec - 14 Dec

A courtyard with outdoor seating, a central fountain, and a view of a tower.

6. The Knight Center at Washington University

2.7 km from North Clayton

April

₹13,521 total

includes taxes & fees

16 Dec - 17 Dec

A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.

7. AC Hotel St. Louis Clayton

0.9 km from North Clayton

Joshua

₹14,126 total

includes taxes & fees

6 Dec - 7 Dec

A rooftop restaurant with round tables, chairs, and a view of the city.

8. Moonrise Hotel

3.7 km from North Clayton

Rebecca

₹15,743 total

includes taxes & fees

16 Dec - 17 Dec

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

9. Hyatt Select St. Louis Airport

9 km from North Clayton

Thadora

₹12,813 total

includes taxes & fees

5 Dec - 6 Dec

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

10. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 5.9 km from North Clayton

Edmond

₹14,491 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

11. Wingate by Wyndham St. Louis Airport

9.7 km from North Clayton

Cindy

₹11,227 total

includes taxes & fees

23 Nov - 24 Nov

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

12. The Cheshire

3.8 km from North Clayton

Matthew

₹16,679 total

includes taxes & fees

22 Nov - 23 Nov

A modern bar area with a central bar counter, seating, and decorative plants.

13. Hampton Inn By Hilton St Louis Airport

9.2 km from North Clayton

Janet

₹12,939 total

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

14. Pear Tree Inn St. Louis Airport

9.7 km from North Clayton

Rebecca

₹10,071 total

includes taxes & fees

19 Nov - 20 Nov

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

15. Drury Inn & Suites St. Louis Airport

9.4 km from North Clayton

Ethan

₹12,825 total

includes taxes & fees

22 Nov - 23 Nov

A modern lobby with a fireplace, comfortable seating, and a large TV screen.

16. Best Western Plus St. Louis West-Westport

11.2 km from North Clayton

Herb

₹9,278 total

includes taxes & fees

19 Nov - 20 Nov

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

17. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 7.5 km from North Clayton

Ruth

₹15,658 total

includes taxes & fees

7 Dec - 8 Dec

A modern lounge area with a stone fireplace, a blue sofa, and a small table.

18. Fairfield Inn & Suites St Louis Westport

10 km from North Clayton

Alan

₹14,458 total

includes taxes & fees

19 Nov - 20 Nov

A buffet with fruits, pastries, and beverages.

19. Renaissance St. Louis Airport Hotel

8.6 km from North Clayton

Joy

₹12,559 total

includes taxes & fees

29 Nov - 30 Nov

A hotel with a covered entrance, a tower with signage, and a landscaped area with planters.

20. La Quinta Inn & Suites by Wyndham St. Louis Westport

9.4 km from North Clayton

Robert

₹7,939 total

includes taxes & fees

3 Dec - 4 Dec

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Compare popular hotels in North Clayton

Property	Property class	Guest rating
Hampton Inn & Suites Clayton/St. Louis-Galleria Area	3.0 star property	8.8 Excellent 1,002 reviews	View
Drury Plaza Hotel St. Louis Brentwood	4.0 star property	9.6 Exceptional 1,002 reviews	View
Courtyard by Marriott St. Louis Brentwood	3.0 star property	9.4 Exceptional 917 reviews	View
Clayton Plaza Hotel & Extended Stay	3.5 star property	8.8 Excellent 3,531 reviews	View
The Knight Center at Washington University	2.5 star property	9.4 Exceptional 726 reviews	View

Where to stay in North Clayton

Find the best North Clayton areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top North Clayton Hotel Reviews

Drury Plaza Hotel St. Louis Brentwood

Brentwood

10/10 Excellent

Andrew

The Knight Center at Washington University

St. Louis

10/10 Excellent

James

Hampton Inn & Suites St. Louis at Forest Park

Dogtown

8/10 Good

john

Hyatt Select St. Louis Airport

Woodson Terrace

8/10 Good

Elisabeth

Pear Tree Inn St. Louis Airport

St. Ann

10/10 Excellent

Stephen

A hotel lobby with a hot tub, a pool, and outdoor seating.

Drury Plaza Hotel St. Louis Creve Coeur

Creve Coeur

10/10 Excellent

Jeffrey

Drury Inn & Suites St. Louis Forest Park

Clifton Heights

10/10 Excellent

Joe

The Cheshire

Richmond Heights

8/10 Good

The property was safe, clean and the staff were friendly. The room was a good size and comfortable. Only negatives were in places it seemed a little tired and the beds particularly were a bit of a hazard as they stuck out at the corners and both myself and my partner bashed our shins a couple of times! I also dont believe the pool was open, though it seemed to be the case on the East side of the US that pools dont open until the end of May. The breakfast included the next day was good and had...

Ryan

Frequently Asked Questions

What is North Clayton like?

Travellers to St. Louis's North Clayton neighbourhood will be sure to enjoy a stay here.

What's a favourite place to stay in North Clayton?

Based on our traveller data, Hampton Inn & Suites Clayton/St. Louis-Galleria Area is one of the top choices for your stay in North Clayton. This hotel offers free breakfast and an indoor pool.

How many hotels will I find in the North Clayton area?

If you're searching for places to stay in St. Louis, choose from one of Expedia's 11 hotels and other accommodation options in North Clayton.

If I need to cancel my hotel reservation in North Clayton, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available in North Clayton.

What is there to do in this St. Louis neighbourhood?

St. Louis Zoo, Shaw Park Tennis Center and Saint Louis Galleria Mall are just a few of the places to visit in and around North Clayton. While you're out sightseeing, Heman Park Tennis Center and Tao Tennis Center are a couple of additional sights to visit in St. Louis.

Search Hotels in North Clayton, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for North Clayton hotels

1. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

2. Drury Plaza Hotel St. Louis Brentwood

3. SpringHill Suites St. Louis Brentwood

4. Courtyard by Marriott St. Louis Brentwood

5. Clayton Plaza Hotel & Extended Stay

6. The Knight Center at Washington University

7. AC Hotel St. Louis Clayton

8. Moonrise Hotel

9. Hyatt Select St. Louis Airport

10. Hampton Inn & Suites St. Louis at Forest Park

11. Wingate by Wyndham St. Louis Airport

12. The Cheshire

13. Hampton Inn By Hilton St Louis Airport

14. Pear Tree Inn St. Louis Airport

15. Drury Inn & Suites St. Louis Airport

16. Best Western Plus St. Louis West-Westport

17. Home2 Suites by Hilton St. Louis/Forest Park

18. Fairfield Inn & Suites St Louis Westport

19. Renaissance St. Louis Airport Hotel

20. La Quinta Inn & Suites by Wyndham St. Louis Westport

Compare popular hotels in North Clayton

Where to stay in North Clayton

Downtown St. Louis

Clayton

St. Charles Historic District

Central West End

Creve Coeur

Top North Clayton Hotel Reviews

Drury Plaza Hotel St. Louis Brentwood

10/10 Excellent

Frequently Asked Questions

What is North Clayton like?

What's a favourite place to stay in North Clayton?

How many hotels will I find in the North Clayton area?

If I need to cancel my hotel reservation in North Clayton, will I receive a refund?

What is there to do in this St. Louis neighbourhood?