Search Hotels in North Clayton, St. Louis

Where to?

Dates

June 2026

July 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Where to stay in North Clayton

Find the best North Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

See properties

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

See properties

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

See properties

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

See properties

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

See properties

Top North Clayton Hotel Reviews

River City Casino & Hotel

10/10 Excellent

"Beautiful place to stay. Helpful staff. Good food.. Clean. Very nice. Would definitely stay again."

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Staff was great. Shuttle was a life saver and worth the money. The shampoo and body wash in the shower would not dispense. King bed very comfortable. Glad there was a safe to use in the room. AV in room worked well. 7th floor at elevators the wall paper was healing away from wall by the buttons. Need more seating at bar before you get to the casino. The dog restaurant inside the casino could have been better but at 1 am your just glad somethings open. Room was clean."

Live by Loews - St.Louis

2/10 Terrible

"I honestly didn’t like anything about it compared to other hotels at the same stars. The room that we paid for supposed two queen size I but they are more like full or double sizes. (4.6-4.9 ft wide to be exact). The sheets had spots on them, same the furniture. I had to call the supervisor to clean some blood spots or something red/brown from the nightstand. the phone had like green toothpaste on it. I have pictures of all of these. I asked to change the room , they refused and sent someone to do a little wiping. like seriously it was the worst experience we had… there were spots on the carpet; just awful! Waste of money and luckily, we stayed only one night… awful view as well. We Supposed to have a courtyard view but we faced a full wall in front of us. Parking valet was $50 or $40 to park yourself. When we stayed at the Four seasons, a night before, the parking was included. The room was nice and clean. Everything was great and for $60 more as you don’t have to pay the parking,it was more it was worth it. Won’t stay at this Live by Lowe again."

Frequently asked questions

What is North Clayton like?

Travellers to St. Louis's North Clayton neighbourhood will be sure to enjoy a stay here.

What's a favourite place to stay in North Clayton?

Based on our traveller data, Hampton Inn & Suites Clayton/St. Louis-Galleria Area is one of the top choices for your stay in North Clayton. This hotel offers free breakfast and an indoor pool.

How many hotels will I find in the North Clayton area?

If you're searching for places to stay in St. Louis, choose from one of Expedia's 11 hotels and other accommodation options in North Clayton.

If I need to cancel my hotel reservation in North Clayton, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available in North Clayton.

What is there to do in this St. Louis neighbourhood?

St. Louis Zoo, Shaw Park Tennis Center and Saint Louis Galleria Mall are just a few of the places to visit in and around North Clayton. While you're out sightseeing, Heman Park Tennis Center and Tao Tennis Center are a couple of additional sights to visit in St. Louis.

Explore a world of travel with Expedia

More ways to book

Book Hotels in North Clayton on Expedia.com

Search Hotels in North Clayton, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for North Clayton hotels

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Super 8 by Wyndham St Charles

Hyatt Select St. Louis Airport

Pear Tree Inn St. Louis Airport

Wingate by Wyndham St. Louis Airport

River City Casino & Hotel

The Principal Hotel

Motel 6 Hazelwood, MO

Drury Inn & Suites St. Louis Airport

Best Western Plus Fenton

Drury Inn & Suites St. Louis St. Peters

Hampton Inn St. Charles St. Peters

Best Western St. Louis Inn

Pear Tree Inn St. Louis Arnold

Wingate by Wyndham St. Louis/Fenton Route 66

The Wildwood Hotel

Drury Plaza Hotel St. Louis at the Arch

Comfort Suites St Charles - St Louis

Best Western Plus Pontoon Beach

Where to stay in North Clayton

Downtown St. Louis

Clayton

Creve Coeur

Central West End

Downtown West

Top North Clayton Hotel Reviews

River City Casino & Hotel

Frequently asked questions

Explore a world of travel with Expedia