A sunset over a beach with a pier extending into the water.

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Check availability on Los Osos Spa Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Los Osos hotels with a spa

A bathroom with a stone sink, a mirror, and towels hanging on the wall.

1. Madonna Inn

Madonna Inn
3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1,623 reviews)
  • cleanliness
    Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.
The price is ₹12,873
₹17,844 total
includes taxes & fees
1 Nov - 2 Nov
Madonna Inn
A multi-story building with balconies, a fountain, and a patio area.

2. Avila La Fonda Hotel

Avila La Fonda Hotel
4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Revitalising seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.
The price is ₹18,263
₹20,546 total
includes taxes & fees
2 Nov - 3 Nov
Avila La Fonda Hotel
A spacious lobby with a wooden ceiling, a reception desk, seating areas, and large windows offering views of the outdoors.

3. Hotel San Luis Obispo

Hotel San Luis Obispo
4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (692 reviews)
  • cleanliness
    Savour serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.
The price is ₹27,536
₹31,253 total
includes taxes & fees
1 Nov - 2 Nov
Hotel San Luis Obispo
A multi-story hotel with balconies, a covered walkway, and a landscaped garden area.

4. The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Revitalise mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.
The price is ₹14,558
₹16,551 total
includes taxes & fees
28 Oct - 29 Oct
The Agrarian Hotel, BW Signature Collection
A room with a dining table, chairs, a hanging plant, and a window with blinds.

5. Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
3.5 star property
Cayucos
9.8 out of 10, Exceptional, (262 reviews)
  • cleanliness
    Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.
The price is ₹16,407
₹18,458 total
includes taxes & fees
29 Oct - 30 Oct
Cayucos Sunset Inn B&B
A modern interior with a reception desk, wooden shelving, and a variety of products on display.

6. HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (505 reviews)
  • cleanliness
    Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.
The price is ₹25,035
₹31,711 total
includes taxes & fees
16 Nov - 17 Nov
HOTEL CERRO, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Los Osos

Pool
Breakfast included

Top Los Osos Hotel Reviews

Cottage Inn By The Sea

Cottage Inn By The Sea

10/10 Excellent
"Very nice view from the pool/fire pit area. We enjoyed our stay very much, just enough far out of pismo beach to enjoy a 10 min walk on the beach to get coffee downtown every morning. Rooms are cozy and clean."
Maude 2-night trip
Posted 3 hours ago
Cottage Inn By The Sea

Frequently asked questions

Looking for a spa hotel in Los Osos?
Forget the stress of everyday life and book yourself a hotel with a spa. Discover the beaches in Los Osos—worth a picture or two! Take part in recreational activities such as golf during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Los Osos?
Sea Pines Resort is a top spa hotel featuring a golf course, a bar and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages and couples treatments.
How many spa hotels will I find in Los Osos?
Among Expedia's 44 accommodation options in Los Osos, there is 1 spa hotel.
What's there to see and do in Los Osos?
Experience Los Osos with a stop at Montaña de Oro State Park, Morro Bay State Park and Los Osos Oaks State Reserve. If you have a bit of extra time while you're in the area, you might want to check out Morro Coast Audubon Society Sweet Springs Nature Preserve and Islay Creek Trail.
What is a Los Osos spa hotel?
Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.