The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis - 2026 Updated Prices

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Murphy

₹8,666

₹10,290 total

includes taxes & fees

12 Oct - 13 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Mary

₹9,322

₹10,975 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

3. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Will

₹10,594

₹13,028 total

includes taxes & fees

15 Oct - 16 Oct

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A pool area with two hot tubs, seating, and a view of the outdoors.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

4. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Lori

₹11,073

₹13,104 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A snack vending machine with various snack options.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

₹12,405

₹14,927 total

includes taxes & fees

15 Oct - 16 Oct

A breakfast buffet with labeled sections for fruit and cereal.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A kitchen area with wooden cabinets, a refrigerator, and shelves stocked with various food items.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

₹11,750

₹14,408 total

includes taxes & fees

1 Nov - 2 Nov

A buffet with fruits, pastries, and beverages.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

7. Renaissance St. Louis Airport Hotel

2 km from James S. McDonnell Prologue Room

Anthony

₹11,378

₹13,311 total

includes taxes & fees

29 Oct - 30 Oct

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Sha

₹13,734

₹16,389 total

includes taxes & fees

30 Oct - 31 Oct

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

₹9,793

₹11,491 total

includes taxes & fees

1 Nov - 2 Nov

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

₹12,846

₹15,459 total

includes taxes & fees

29 Oct - 30 Oct

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Annalyn

₹6,303

₹7,447 total

includes taxes & fees

1 Nov - 2 Nov

A reception desk with a cityscape on the monitor, a blue-lit ceiling, and a sign for key drop-off.

A hotel room with a large bed, two bedside tables, a TV, a desk, and a window with curtains.

Two white front-loading washers stacked on top of each other with a Gain detergent box and a Whirlpool instruction manual on the top washer.

A restaurant with tables and chairs, a coffee machine, and a refrigerator.

12. Travelodge by Wyndham St. Louis

2.4 km from James S. McDonnell Prologue Room

LIXIN

₹6,067

₹7,180 total

includes taxes & fees

25 Oct - 26 Oct

A parking lot with multiple cars, a building with a green and beige facade, and a sign for Home Towne Studios.

A compact kitchenette with a sink, stove, microwave, and a white refrigerator.

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

₹6,548

₹8,004 total

includes taxes & fees

7 Oct - 8 Oct

A hotel room with a large bed, bedside tables, a heater, and a view of the city.

A modern living room with a grey sofa, a red bench, a dark wooden table, and a TV on a stand.

A multi-story brick building with a central entrance, parking lot, and designated handicapped parking spaces.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

14. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Fed

₹7,222

₹8,829 total

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

15. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

₹5,335

₹6,636 total

includes taxes & fees

25 Oct - 26 Oct

A hotel lobby with a hot tub, a pool, and outdoor seating.

A lobby with seating areas, a reception desk, and a view of the lobby in the background.

A large conference room with rows of chairs, a patterned carpet, and a ceiling with recessed lighting and a chandelier.

A modern coffee shop interior with wooden furniture, a coffee bar, and a sign for 'KELSO+BROS Coffee Roasters'.

16. Drury Plaza Hotel St. Louis Creve Coeur

Creve Coeur, 12.5 km from James S. McDonnell Prologue Room

Eryn

₹12,615

₹14,664 total

includes taxes & fees

11 Oct - 12 Oct

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

A hotel room with two beds, a desk, and a chair.

17. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

Rosalyn

₹16,291

₹18,732 total

includes taxes & fees

11 Oct - 12 Oct

A rooftop restaurant with round tables, chairs, and a view of the city.

A modern lobby with a staircase, seating area, and wall-mounted artwork.

A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.

A modern lobby with a staircase, seating area, and an exit sign.

18. Moonrise Hotel

11.2 km from James S. McDonnell Prologue Room

Katherine

₹12,710

₹15,117 total

includes taxes & fees

28 Oct - 29 Oct

A brick building with a sign reading "Country Inn & Suites."

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

19. Country Inn & Suites by Radisson, St. Charles Historic District

12.5 km from James S. McDonnell Prologue Room

Roseanna

₹12,791

₹14,700 total

includes taxes & fees

1 Nov - 2 Nov

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A living room with a brown leather sofa, a small table, and a chair. There is a window with curtains, a lamp, and a framed picture on the wall.

A hotel room with two beds, a desk, a chair, and a television.

A large conference room with rows of tables and chairs, a podium, and a buffet table with plates and napkins.

20. Clayton Plaza Hotel & Extended Stay

11.2 km from James S. McDonnell Prologue Room

Sivakumar

₹8,824

₹10,301 total

includes taxes & fees

25 Oct - 26 Oct

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,290 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,709 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,010 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,437 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 231 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Perfect for early morning flight."

Hyatt Select St. Louis Airport

10/10 Excellent

"This is a great place to stay at !"

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Outstanding experience."

Wingate by Wyndham St. Louis Airport

10/10 Excellent

"."

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"My flight out of St. Louis was cancelled, so I needed to find lodging quickly. This was a great option. Super clean and the shuttle goes straight to the airport, not multi-stop. I had a great meal, in the Hilton next door and enjoyed a college football game in the spacious bar/dining room."

Marriott St. Louis Airport

8/10 Good

"There was a huge conference in town so rooms were a premium. We had scheduled our plans a bit late so we didn’t get the exact rooms we booked. But the staff did a great job in getting us as close as possible and made nice concessions for the inconveinence."

Renaissance St. Louis Airport Hotel

10/10 Excellent

"I have no complaints about this hotel. The staff was pleasant and helpful. It was wonderfully clean throughout. The Renaissance Hotel has my highest recommendation as a wonderful place to stay."

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art galleries.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you take a trip to Payne-Gentry Historical House. Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine during your travels in Florissant. Experience the great live music and acclaimed theatre scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time studying the exhibits at St. Louis Car Museum during your travels in Overland. Experience the acclaimed theatre scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time exploring the galleries in St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theatre scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your stay in St. Louis. Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I be able to find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodation options a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best options available near James S. McDonnell Prologue Room.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're out exploring.

Search Hotels Near James S. McDonnell Prologue Room, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Hyatt Select St. Louis Airport

4. Drury Inn & Suites St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. Travelodge by Wyndham St. Louis

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

14. Welcome Suites Hazelwood

15. Quality Inn Saint Louis Airport

16. Drury Plaza Hotel St. Louis Creve Coeur

17. The Knight Center at Washington University

18. Moonrise Hotel

19. Country Inn & Suites by Radisson, St. Charles Historic District

20. Clayton Plaza Hotel & Extended Stay

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

Hyatt Select St. Louis Airport

Drury Inn & Suites St. Louis Airport

Wingate by Wyndham St. Louis Airport

Hampton Inn By Hilton St Louis Airport

Marriott St. Louis Airport

Renaissance St. Louis Airport Hotel

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions