TOP Business Hotels in Eastern South Dakota, SD for 2026

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Our top choices for Eastern South Dakota business-friendly hotels

An outdoor patio with a round table and wicker chairs, a fire pit, and a brick wall.

A modern living room with a stone fireplace, comfortable seating, and a large window offering a city view.

A modern hotel lobby with a reception desk, seating area, and a stone fireplace.

1. Fairfield Inn & Suites Sioux Falls Airport

Northwest Sioux Falls

Penny

₹8,571

₹9,596 total

includes taxes & fees

11 Oct - 12 Oct

A swimming pool with clear blue water, surrounded by a tiled deck and a seating area with chairs and tables.

A hotel room with a bed, a sofa, a desk, and a chair.

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a clear view of the building's facade.

A modern hotel room with a kitchenette, a sofa, a dining table, a small round table, a bed, and a view of the outdoors.

2. Comfort Inn & Suites at Sanford Sports Complex

Northwest Sioux Falls

jason

₹9,774

₹10,914 total

includes taxes & fees

18 Oct - 19 Oct

A La Quinta Inn & Suites building with a covered entrance and multiple windows.

A hotel room with a large bed, a desk, a chair, a TV, and a minibar.

A swimming pool with a tiled deck, lounge chairs, and a sunroof.

A hotel lobby with a dining area, seating area, and a TV mounted on the wall.

3. La Quinta Inn & Suites by Wyndham Sioux Falls

Mall District

Kathy

₹9,448

₹10,556 total

includes taxes & fees

11 Oct - 12 Oct

A large, two-story building with a stone facade and multiple windows, illuminated by warm lighting.

An indoor swimming pool with a water slide, a large umbrella structure, and a frog-shaped water feature.

A stone pillar with a fire pit in the center, surrounded by blue chairs.

A spacious lobby with a central seating area, a staircase, and a fireplace.

4. Clubhouse Hotel Suites Sioux Falls

Mall District

Jordyn

₹12,803

₹15,360 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with two beds, a desk, a TV, and a staircase leading to an upper level.

A kitchen with a refrigerator, a coffee machine, a toaster, and a display case with pastries.

A reception area with a wooden reception desk, a sign reading "AmerInn by Wyndham", a refrigerator stocked with beverages, and a snack shelf.

A swimming pool with a tiled deck, lounge chairs, and a small table with chairs.

5. AmericInn by Wyndham Sioux Falls North

Northwest Sioux Falls

Richard

₹9,578

₹10,699 total

includes taxes & fees

4 Oct - 5 Oct

A deck with outdoor furniture, a fire pit, and a view of a body of water.

A modern hotel lobby with a dining area, seating arrangements, and a kitchen in the background.

A reception area with a herringbone-patterned wall, a reception desk, and seating area with chairs and a table.

A modern bar area with seating, a counter with a beverage display, and a large window providing a view.

6. Hyatt Place Sioux Falls South

Mall District

Catherine

₹11,212

₹12,491 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a blue sofa, a nightstand with a lamp, and a mural of a waterfall on the wall.

A hotel lobby with a fireplace, seating area, and a bar.

A multi-story hotel with a covered entrance, brick facade, and a large tree in front.

A hotel reception area with a large mural of a mountain and a clear view of the lobby.

7. Clarion Pointe Sioux Falls Airport

Northwest Sioux Falls

Rachel

₹8,653

₹9,685 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel lobby with seating areas, a bar, and a kitchen visible in the background.

A hotel exterior with stone facade, outdoor seating area, and a neon sign.

A modern hotel dining area with a central island, high chairs, and a kitchen counter.

A snack display area with various chips and snacks, a 'Treats' sign, and a beverage refrigerator.

8. Hampton Inn & Suites Southwest/Sioux Falls

South Sioux Falls

Hettianne

₹10,560

₹11,777 total

includes taxes & fees

1 Nov - 2 Nov

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Top Eastern South Dakota Hotel Reviews

Super 8 by Wyndham Sioux Falls/41st Street

10/10 Excellent

"Amazing people and breakfast"

Clubhouse Hotel Suites Sioux Falls

10/10 Excellent

"Great stay. Quiet room! Nice breakfast!"

Days Inn by Wyndham Sioux Falls Empire

10/10 Excellent

"No continental breakfast but the restaurant is REALLY GOOD! Recommend go try the Chislic, Calamari and drinks for dinner. Breakfast is inexpensive as well. Room is spacious!"

Baymont by Wyndham Sioux Falls

8/10 Good

"Great room at an even better price."

Days Inn by Wyndham Mitchell SD

10/10 Excellent

"Breakfast included scrambled eggs, sausage, and a variety of pastries."

Kelly Inn & Suites Mitchell South Dakota

10/10 Excellent

"It was clean and nice. Breakfast was good"

Frequently asked questions

How much do business-friendly hotels in Eastern South Dakota cost?

Rates for business hotels in Eastern South Dakota range between ₹6,632 and ₹15,523 per night. No matter your budget, Expedia can help you find the ideal space to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Eastern South Dakota?

There are multiple business-friendly hotels in Eastern South Dakota with a total average guest review rating of 9.4, so you're sure to find a place that suits your needs. Heading to Sioux Falls? Hotel On Phillips is a top choice for corporate travellers. This 2.5-stars option includes amenities such as pillow top mattresses and a Champagne service. Fairfield Inn & Suites Sioux Falls Airport also scores top marks from business guests. Make use of pillow top mattresses and a swimming pool at this 3-stars escape in Sioux Falls.

How many business-friendly hotels are there in Eastern South Dakota?

There are 114 business-friendly hotels in Eastern South Dakota. When work takes you out of town, Expedia makes it easy to find the ideal space with the amenities you want.

What are the best cheap business-friendly hotels in Eastern South Dakota?

That depends on which part of Eastern South Dakota work is taking you. If you're off to Sioux Falls, Hotel On Phillips meets the needs of business travellers at an affordable price. Pillow top mattresses and a cafe are among its many conveniences. On your way to Mitchell? Consider staying at Hampton Inn Mitchell. A swimming pool and designer toiletries help make this cheaper property a top pick for corporate visitors. Business-friendly hotels start at ₹6,632 per night, so that important work trip doesn't have to stretch your finances. Eager to see the sights of Eastern South Dakota without blowing the budget? Take a break from your work events to visit popular free attractions like St. Joseph Cathedral in Sioux Falls. Mitchell also has loads of things to do that don't cost a dime, including Dakota Discovery Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Eastern South Dakota that are also business friendly?

If you're travelling for business in Eastern South Dakota and bringing the family along with you, Expedia will help you locate a cosy and convenient stay. Clubhouse Hotel Suites Sioux Falls in Sioux Falls is an excellent option for those juggling work and leisure. This 3-stars property comes with all the amenities you'll need, like complimentary breakfast and a children's pool. Holiday Inn & Suites Sioux Falls - Airport, an IHG Hotel is another fantastic choice in Sioux Falls. Enjoy the best of both worlds — combine corporate travel and quality time with your family at this 3-stars property. WiFi and laundry facilities are just two of the many conveniences you'll find here. When you've finished work, it's time to explore Sioux Falls with the kids. Popular family-friendly attractions include Great Plains Zoo and Wild Water West.

Why book your business-friendly hotel in Eastern South Dakota with Expedia?

With conveniences like meeting rooms, 24-hour room service and on-site restaurants, our business-friendly properties come with everything you'll need to settle that big contract — and then chill! Enter your preferred dates and travel destination and Expedia will help you with everything else.

How can I find cheap business-friendly hotels in Eastern South Dakota?

When work takes you to Eastern South Dakota, our "business friendly" filter will help you find the perfect hotel. From included breakfast and free WiFi to meeting rooms and workspaces, they come with the amenities you need to get the job done. Another tip? Narrow your search by your budget and preferred star rating to view the most affordable accommodation.

What is there to do in Eastern South Dakota near my business-friendly hotel?

There are so many things to keep you entertained in Eastern South Dakota. If you're off to Sioux Falls, you'll want to check out Great Plains Zoo, Washington Pavilion of Arts and Science and St. Joseph Cathedral. Planning to stay in Mitchell? Dakota Discovery Museum, Corn Palace and Mitchell Aquatic Centre are popular attractions here.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Eastern South Dakota Business Hotels

Our top choices for Eastern South Dakota business-friendly hotels

1. Fairfield Inn & Suites Sioux Falls Airport

2. Comfort Inn & Suites at Sanford Sports Complex