What is Downtown like?

Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Seneca Historic District and Bertha Lee Strickland Cultural Museum as part of your Downtown travel plans.

Where is the best place to stay in Downtown?

Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.

How many hotels will I be able to find in Downtown?

Expedia has 9 Downtown hotels and other accommodation options, and one might make a good home base for venturing out into the greater Seneca area.

If I need to cancel my hotel reservation in Downtown, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.

What can I see and do in this Seneca neighbourhood?

Seneca Historic District, Bertha Lee Strickland Cultural Museum and Oconee County Library Seneca Branch are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, The Gauntlet and Seneca City Hall are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Wyndham Plaza or Cross Creek Plantation Golf.

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Dates

January 2026

17

February 2026

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Our top choices for Downtown hotels

Lakeside Lodge Clemson

8.6 km from Downtown

Gene

₹12,218 total

includes taxes & fees

19 Jan - 20 Jan

Best Western Plus Clemson Hotel & Conference Center

11.8 km from Downtown

Audrey

₹9,286 total

includes taxes & fees

19 Jan - 20 Jan

Comfort Suites Anderson-Clemson

25.3 km from Downtown

jose

₹10,994 total

includes taxes & fees

18 Jan - 19 Jan

The Inn at Patrick Square

15.2 km from Downtown

Joyce

₹14,934 total

includes taxes & fees

18 Jan - 19 Jan

Inn @ Clemson

11.6 km from Downtown

Stacey

Hampton Inn & Suites Seneca-Clemson Area

2.2 km from Downtown

Jose

₹11,787 total

includes taxes & fees

25 Jan - 26 Jan

Clemson University's James F. Martin Inn

10.3 km from Downtown

Mindi

₹14,934 total

includes taxes & fees

19 Jan - 20 Jan

Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout curtains, iron/ironing board

Best Western Seneca-Clemson

1.7 km from Downtown

Tabatha

₹9,202 total

includes taxes & fees

25 Jan - 26 Jan

Microtel Inn & Suites by Wyndham Anderson/Clemson

24.8 km from Downtown

Caressa

₹7,582 total

includes taxes & fees

19 Jan - 20 Jan

Tru by Hilton Seneca Clemson

8.3 km from Downtown

Cindy

₹10,425 total

includes taxes & fees

25 Jan - 26 Jan

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace

Comfort Inn & Suites Clemson - University Area

11.7 km from Downtown

Olga

₹9,456 total

includes taxes & fees

25 Jan - 26 Jan

Country Inn & Suites by Radisson, Anderson, SC

25.2 km from Downtown

Sheri

₹11,636 total

includes taxes & fees

23 Jan - 24 Jan

Rodeway Inn Anderson North - Clemson

25.5 km from Downtown

Benito

₹6,515 total

includes taxes & fees

19 Jan - 20 Jan

The Shepherd Hotel Downtown Clemson

10.6 km from Downtown

Shannon

₹17,941 total

includes taxes & fees

19 Jan - 20 Jan

Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub

Days Inn by Wyndham Anderson

25.6 km from Downtown

Michael

₹6,304 total

includes taxes & fees

19 Jan - 20 Jan

Hampton Inn Clemson-University Area

9.8 km from Downtown

Edye

₹10,990 total

includes taxes & fees

25 Jan - 26 Jan

Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers

Fairfield Inn & Suites by Marriott Anderson Clemson

25 km from Downtown

Laura Jo

₹8,434 total

includes taxes & fees

25 Jan - 26 Jan

The Abernathy of Clemson

10.1 km from Downtown

Megan

Quality Inn Clemson near University

29.6 km from Downtown

Alejandro

₹4,644 total

includes taxes & fees

27 Jan - 28 Jan

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

25 km from Downtown

Veronica

₹10,323 total

includes taxes & fees

24 Jan - 25 Jan

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Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

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Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.

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Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Seneca Historic District.

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Keowee Plantation

While Keowee Plantation isn't home to many top sights, Seneca Historic District and Keowee Reservoir are some notable places to visit nearby.

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Top Downtown Hotel Reviews

Days Inn by Wyndham Anderson

10/10 Excellent

"We stayed at this hotel over the weekend to celebrate our anniversary, and it turned into one of the best hotel experiences we’ve ever had. My fiancée and I were looking for something special, and Jennifer suggested their decorated room for occasions like this. I trusted her recommendation, and I’m so glad I did. The moment we walked into the room, we were honestly amazed. It was beautifully decorated from top to bottom. The bed setup was perfect, the details were thoughtful, and the atmosphere felt romantic and relaxing. The jacuzzi tub inside the bedroom was the highlight. It made the whole experience feel extra special. We truly enjoyed every moment of our stay and created memories we’ll always remember. I would highly recommend this hotel to anyone celebrating a special occasion."