A large lake surrounded by dense forests.

Search Hotels in Downtown, Seneca

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Downtown hotels

A poolside area with outdoor seating and a view of a lake and forested hills.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (277 reviews)
"The rooms were very clean and comfortable. Breakfast was outstanding good selection. I love the tranquility of this hotel."
United States
Angela
The price is ₹11,496
₹12,646 total
includes taxes & fees
11 Oct - 12 Oct
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
2.2 km from Downtown
9.2 out of 10, Wonderful, (749 reviews)
"We had a great stay. Nice staff and good breakfast."
United States
Lisa
The price is ₹11,637
₹12,801 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Seneca-Clemson Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.

3. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
3.8 km from Downtown
8.0 out of 10, Very good, (755 reviews)
"Comfortable bed, great pillows, and strong water pressure with plenty of hot water."
United States
Julie
The price is ₹7,245
₹8,546 total
includes taxes & fees
11 Oct - 12 Oct
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

4. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very good, (689 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
The price is ₹9,006
₹9,906 total
includes taxes & fees
28 Oct - 29 Oct
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.

5. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (786 reviews)
"Staff were nice and accommodating"
United States
Rosario
The price is ₹7,475
₹8,222 total
includes taxes & fees
4 Oct - 5 Oct
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.

6. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (896 reviews)
"Staff was great! Room was clean!"
United States
Gretchen
The price is ₹10,137
₹11,150 total
includes taxes & fees
11 Oct - 12 Oct
Tru by Hilton Seneca Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

7. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,001 reviews)
"Great location. Amenities were spot on restaurant staff excellent!"
United States
Lori
The price is ₹10,106
₹12,574 total
includes taxes & fees
4 Oct - 5 Oct
Lakeside Lodge Clemson
A golf course with a water body, trees, and a distant view of a bridge.

8. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,012 reviews)
"Great property!"
United States
Lilllian
The price is ₹14,278
₹15,849 total
includes taxes & fees
4 Oct - 5 Oct
Clemson University's James F. Martin Inn
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

9. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (650 reviews)
"Great location, friendly staff, and large rooms."
United States
Robert
The price is ₹14,512
₹16,108 total
includes taxes & fees
19 Oct - 20 Oct
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

10. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (893 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is ₹17,825
₹19,786 total
includes taxes & fees
7 Oct - 8 Oct
The Shepherd Hotel Downtown Clemson
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

11. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (993 reviews)
"Wonderful place to stay."
United States
John
The price is ₹12,362
₹13,722 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Clemson by IHG
A modern kitchen area with a bar counter and seating.

12. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
9.8 km from Downtown
8.8 out of 10, Excellent, (650 reviews)
"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "
United States
Blaise
The price is ₹10,507
₹11,663 total
includes taxes & fees
9 Oct - 10 Oct
Hampton Inn Clemson-University Area
Room

13. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,002 reviews)
"Great stay. Clean and conveniently located."
United States
Yvette
The price is ₹10,478
₹11,631 total
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn & Suites Clemson - University Area
A modern bar area with a menu board, bar stools, and a countertop with various items.

14. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
12.9 km from Downtown
9.0 out of 10, Wonderful, (581 reviews)
"The staff were so friendly and accommodating. The property was very clean and room was spacious."
United States
kim
The price is ₹12,915
₹14,336 total
includes taxes & fees
11 Oct - 12 Oct
Courtyard Marriott Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

15. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.0 out of 10, Very good, (1,001 reviews)
"Great place to stay."
United States
David
The price is ₹9,693
₹10,759 total
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus Clemson Hotel & Conference Center
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

16. Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.0 out of 10, Very good, (1,007 reviews)
"Great breakfast and location"
United States
Terry
The price is ₹7,215
₹8,009 total
includes taxes & fees
5 Oct - 6 Oct
Inn @ Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

17. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (107 reviews)
"Me and my family had a great time"
United States
Nirumol
The price is ₹8,957
₹14,090 total
includes taxes & fees
1 Nov - 2 Nov
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

18. The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (923 reviews)
"The staff were so friendly and helpful! Love the boutique style hotel vibe with some good restaurants just steps away!"
United States
Jane
The price is ₹14,278
₹15,849 total
includes taxes & fees
4 Oct - 5 Oct
The Inn at Patrick Square
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

19. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
12.5 km from Downtown
6.8 out of 10, (233 reviews)
"While my room was very clean, there was a large stain on the upholstered chair by the window. The picture was missing the bottom part of the frame. The bathroom was old, with a cigarette stain on the tub. Staff were friendly and helpful but it took longer than usual to check in. There was no pepper in the breakfast area and the juice machine was broken. All said and done, I had what I needed. It is a poor economy for all which may explain the shortcomings."
United States
Cynthia
The price is ₹7,676
₹8,520 total
includes taxes & fees
4 Oct - 5 Oct
Days Inn by Wyndham Clemson
A kitchen with a coffee maker, microwave, and refrigerator.

20. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (197 reviews)
"Good value for the price. Bed was comfortable and the price was good"
United States
Richard
The price is ₹7,367
₹8,214 total
includes taxes & fees
31 Oct - 1 Nov
Rodeway Inn & Suites Walhalla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.
A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Keowee Reservoir.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Keowee Reservoir are some notable places to visit nearby.

Top Downtown Hotel Reviews

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

10/10 Excellent
"Clean room amazing staff parking and breakfast"
Heather 1-night trip
Posted 3 hours ago
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.
How many hotels will I be able to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodation options in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Oconee County Library Seneca Branch, Blue Ridge Arts Center and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Applewood Shopping Center or Wyndham Plaza.