A cityscape at dusk with illuminated buildings and a sunset sky.

Search Hotels in Downtown Santa Ana, Santa Ana

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Downtown Santa Ana hotels

A hotel lobby with seating areas, a reception desk, and a large window offering a view of the outside.

1. Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North
2.5 star property
4.3 km from Downtown Santa Ana
8.6 out of 10, Excellent, (1,949 reviews)
"Great stay"
United States
Sheri
The price is ₹10,928
₹12,348 total
includes taxes & fees
13 Oct - 14 Oct
Best Western Plus Orange County Airport North
A hotel room with a bed, a desk, a chair, a lamp, a TV, and a window with a view of trees.

2. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

Holiday Inn Santa Ana-Orange Co. Arpt by IHG
3.0 star property
4.5 km from Downtown Santa Ana
8.8 out of 10, Excellent, (1,616 reviews)
"Convenient location to Airport and other amenities. I've stayed here a couple times and usually pick it if I'm in the area."
United States
Camilla
The price is ₹11,378
₹12,879 total
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Santa Ana-Orange Co. Arpt by IHG
A stone fire pit surrounded by palm trees and chairs in an outdoor seating area.

3. MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels
2.5 star property
4.3 km from Downtown Santa Ana
8.0 out of 10, Very good, (2,280 reviews)
"Good place to stay"
United States
Yvonne
The price is ₹8,934
₹10,113 total
includes taxes & fees
1 Nov - 2 Nov
MainStay Suites John Wayne Airport by Choice Hotels
A modern bar area with a wooden counter, orange bar stools, and a flat-screen TV mounted on the wall.

4. La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport
3.0 star property
4.4 km from Downtown Santa Ana
7.8 out of 10, Good, (2,150 reviews)
"Nice place to stay"
United States
Chanho
The price is ₹8,825
₹9,972 total
includes taxes & fees
18 Oct - 19 Oct
La Quinta Inn & Suites by Wyndham Orange County Airport
A spacious living area with a large wooden table, comfortable seating, a fireplace, and decorative plants.

5. Ayres Hotel Orange

Ayres Hotel Orange
3.5 star property
5 km from Downtown Santa Ana
9.6 out of 10, Exceptional, (3,118 reviews)
"We have stayed here a few times and have enjoyed every one of them."
United States
Anne
The price is ₹12,063
₹13,292 total
includes taxes & fees
1 Nov - 2 Nov
Ayres Hotel Orange
A hotel room with two beds, a bathroom, and a view of a bridge.

6. Orange Grove Inn

Orange Grove Inn
2.5 star property
5.5 km from Downtown Santa Ana
9.2 out of 10, Wonderful, (2,712 reviews)
"Best place to stay at"
United States
jocelyn
The price is ₹7,810
₹8,841 total
includes taxes & fees
26 Oct - 27 Oct
Orange Grove Inn
An outdoor seating area with fire pits, modern furniture, and a view of the sky.

7. Hotel Fera Anaheim, a DoubleTree by Hilton

Hotel Fera Anaheim, a DoubleTree by Hilton
4.0 star property
5.1 km from Downtown Santa Ana
8.8 out of 10, Excellent, (4,790 reviews)
"Great place to stay"
United States
Ahmad
The price is ₹12,212
₹13,457 total
includes taxes & fees
13 Oct - 14 Oct
Hotel Fera Anaheim, a DoubleTree by Hilton
A modern living room with a staircase, a sofa, and a small dining area.

8. Lemon Heights Inn

Lemon Heights Inn
2.5 star property
5.4 km from Downtown Santa Ana
9.4 out of 10, Exceptional, (1,011 reviews)
"Great stay"
United States
Saurav
The price is ₹8,505
₹9,610 total
includes taxes & fees
11 Oct - 12 Oct
Lemon Heights Inn
A grocery store with shelves stocked with snacks, beverages, and frozen goods.

9. Hampton Inn & Suites Irvine-Orange County Airport

Hampton Inn & Suites Irvine-Orange County Airport
3.0 star property
8.1 km from Downtown Santa Ana
9.2 out of 10, Wonderful, (1,058 reviews)
"Close to the airport. Spacious room and decent included breakfast. Would stay here again for the price."
United States
Nicole
The price is ₹12,572
₹13,854 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Irvine-Orange County Airport
A hotel lobby with multiple seating areas, palm trees, and a large glass facade.

10. Hyatt Regency Orange County

Hyatt Regency Orange County
4.0 star property
6.4 km from Downtown Santa Ana
9.2 out of 10, Wonderful, (6,026 reviews)
"Amazing place to stay and close to so many sights"
United States
Amanda
The price is ₹12,410
₹16,800 total
includes taxes & fees
12 Oct - 13 Oct
Hyatt Regency Orange County
A hotel with a dome and arched windows, a covered entrance, and palm trees.

11. Hotel Marguerite Anaheim/Garden Grove, Trademark Collection by Wyndham

Hotel Marguerite Anaheim/Garden Grove, Trademark Collection by Wyndham
2.5 star property
4.7 km from Downtown Santa Ana
8.2 out of 10, Very good, (1,593 reviews)
"Great stay 15 min drive from Disney would recommend staff was great"
United States
Triston
The price is ₹11,021
₹12,640 total
includes taxes & fees
18 Oct - 19 Oct
Hotel Marguerite Anaheim/Garden Grove, Trademark Collection by Wyndham
A multi-level hotel lobby with a central pool, seating areas, and a modern architectural design.

12. Embassy Suites by Hilton Anaheim South

Embassy Suites by Hilton Anaheim South
3.5 star property
6.6 km from Downtown Santa Ana
8.6 out of 10, Excellent, (3,213 reviews)
"Great place to stay nice clean rooms are great and the breakfast amazing"
United States
Gina
The price is ₹11,386
₹13,344 total
includes taxes & fees
25 Oct - 26 Oct
Embassy Suites by Hilton Anaheim South
A modern interior with a large glass wall, a dining area with a long table and chairs, a sofa set, and a staircase.

13. Sonesta Irvine John Wayne Airport

Sonesta Irvine John Wayne Airport
3.5 star property
7.6 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (1,508 reviews)
"Absolutely loved my stay"
United States
Dwayne
The price is ₹12,342
₹15,726 total
includes taxes & fees
30 Oct - 31 Oct
Sonesta Irvine John Wayne Airport
A modern restaurant with a sunset mural, contemporary furniture, and a view of the ocean.

14. Hyatt Regency Irvine

Hyatt Regency Irvine
4.0 star property
8.2 km from Downtown Santa Ana
9.4 out of 10, Exceptional, (1,195 reviews)
"Such a beautiful stay"
United States
CRISTOFER
The price is ₹21,599
₹23,801 total
includes taxes & fees
16 Oct - 17 Oct
Hyatt Regency Irvine
A bar with hanging plants, a mural, and shelves of bottles.

15. ALO Hotel by Ayres, Orange

ALO Hotel by Ayres, Orange
3.5 star property
5.1 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (2,812 reviews)
"Great stay, always stay here when in the area"
United States
Francisco
The price is ₹10,327
₹11,380 total
includes taxes & fees
1 Nov - 2 Nov
ALO Hotel by Ayres, Orange
A spacious lobby with a fireplace, seating area, and a large wooden cabinet.

16. Ayres Hotel Anaheim

Ayres Hotel Anaheim
3.5 star property
6.6 km from Downtown Santa Ana
9.4 out of 10, Exceptional, (2,369 reviews)
"Over all nice clean rooms breakfast was awesome staff friendly"
United States
Guadlupe
The price is ₹11,195
₹13,125 total
includes taxes & fees
2 Nov - 3 Nov
Ayres Hotel Anaheim
A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and artwork on the walls.

17. Delta Hotels by Marriott Anaheim Garden Grove

Delta Hotels by Marriott Anaheim Garden Grove
3.5 star property
6.2 km from Downtown Santa Ana
8.6 out of 10, Excellent, (2,060 reviews)
"Staff great and clean room"
United States
Melinna
The price is ₹10,671
₹12,506 total
includes taxes & fees
29 Oct - 30 Oct
Delta Hotels by Marriott Anaheim Garden Grove
An indoor swimming pool with a high ceiling, visible structural beams, and a central water slide.

18. Great Wolf Lodge Anaheim, CA

Great Wolf Lodge Anaheim, CA
3.5 star property
5.6 km from Downtown Santa Ana
8.4 out of 10, Very good, (2,072 reviews)
"Great place for family"
United States
Sergio
The price is ₹15,327
₹17,732 total
includes taxes & fees
21 Oct - 22 Oct
Great Wolf Lodge Anaheim, CA
A Sheraton hotel with a symmetrical facade, multiple floors, and a central entrance.

19. Sheraton Garden Grove-Anaheim South Hotel

Sheraton Garden Grove-Anaheim South Hotel
3.5 star property
6 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (2,005 reviews)
"Clean room good helpful staff great location"
United States
Uila M
The price is ₹12,212
₹14,312 total
includes taxes & fees
25 Oct - 26 Oct
Sheraton Garden Grove-Anaheim South Hotel
A hotel lobby with yellow seating, a reception desk, and a visible 'Wyndham Hotel' sign.

20. Wyndham Anaheim

Wyndham Anaheim
3.5 star property
7.5 km from Downtown Santa Ana
9.6 out of 10, Exceptional, (1,874 reviews)
"Great stay"
United States
Makayla
The price is ₹17,786
₹20,809 total
includes taxes & fees
1 Nov - 2 Nov
Wyndham Anaheim
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown Santa Ana

Find the best Downtown Santa Ana areas for the activities you enjoy most.
A sprawling urban area with a prominent highway, surrounded by residential neighborhoods and distant mountains.

North Tustin

While North Tustin isn't home to many top sights, The Market Place and Irvine Regional Park are some notable places to visit nearby.

An aerial view of a city with a river, bridges, and a highway.

Riverview West

While Riverview West may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like David L. Baker Memorial Golf Center and Mile Square Regional Park.

A large dinosaur skeleton exhibit with a prominent skull in the foreground and a massive tail structure in the background.

Park Santiago

While visiting Park Santiago, you might make a stop by sights like Discovery Science Center and Santiago Park.

A blue and yellow parrot with a black beak and white face, perched on a branch.

Lyon Street

While Lyon Street isn't home to many top sights, Santa Ana Zoo and Cabrillo Tennis Center are some notable places to visit nearby.

Riverview

While Riverview may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bowers Museum and The Outlets at Orange.

Top Downtown Santa Ana Hotel Reviews

Hotel Lulu, BW Premier Collection

Hotel Lulu, BW Premier Collection

8/10 Good
"Showing it’s age but near parks"
Liliana 3-night trip
Posted 8 hours ago
Hotel Lulu, BW Premier Collection

Frequently asked questions

What is Downtown Santa Ana like?
Guests are sure to enjoy their time checking out all that Santa Ana's Downtown Santa Ana neighbourhood has to offer. Are you looking for Downtown Santa Ana travel tips? Make sure that you visit Santora Arts Building and 4th Street Market while you're in the neighbourhood.
How many hotels will I be able to find in the Downtown Santa Ana area?
When you want to put your feet up after a day of exploring the sights in Santa Ana, you can choose from 10 Expedia hotels and other accommodation options in Downtown Santa Ana.
If I need to cancel my hotel reservation in Downtown Santa Ana, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the best options available in Downtown Santa Ana.
What are the top things to see and do in Downtown Santa Ana?
A few attractions you might want to check out while you're in Downtown Santa Ana are Santora Arts Building and 4th Street Market. Old Orange County Courthouse and Dr. Willella Howe-Waffle House and Medical Museum are also worth a visit when you're out sightseeing in Santa Ana.