Compare and book 5 Star hotels in Northeast Missouri, Missouri
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Top Northeast Missouri 5 Star Hotels

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
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Moonrise Hotel
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Great live music, sports teams and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theatres.

Find out more about Northeast Missouri
Find out more about Northeast Missouri
Stay in Luxury: 5 Star Hotels in Northeast Missouri
There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Northeast Missouri trip. You'll join the multitudes of holidaymakers who have made Northeast Missouri so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Northeast Missouri and indulge in the finer things in life for a while.
5-Star Hotels in Northeast Missouri
You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Northeast Missouri are waiting for you to relax after an exciting day.
Make Your Escape
The results are in, and Northeast Missouri 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Northeast Missouri! Choose one of our Northeast Missouri 5-star hotels today and soothe yourself in luxe surroundings at your convenience.
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Hotels in Northeast Missouri by Star Rating
Accommodation near Northeast Missouri attractions
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near Enterprise Center
- Hotels near Dome at America’s Center
- Hotels near Forest Park
- Hotels near Barnes Jewish Hospital
- Hotels near Hollywood Casino Amphitheatre
- Hotels near America's Center Convention Complex
- Hotels near St. Louis University
- Hotels near Mississippi River
- Hotels near Westport Plaza
- Hotels near Ameristar Casino St. Charles
- Hotels near Fox Theater
- Hotels near Meramec Caverns
- Hotels near St Charles Convention Center
- Hotels near Grant's Farm
- Hotels near St. Louis Aquarium at Union Station
- Hotels near Magic House - St. Louis Children's Museum
Choose Your Northeast Missouri Hotel Style
- Business Hotels in Northeast Missouri
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- Golf Hotels in Northeast Missouri
- Historic Hotels in Northeast Missouri
- Hotels Suites in Northeast Missouri
- Hotels near Museums in Northeast Missouri
- Hotels with Air Conditioning in Northeast Missouri
- Hotels with Breakfast in Northeast Missouri
- Hotels with Connecting Rooms in Northeast Missouri
- Hotels with Entertainment in Northeast Missouri
- Hotels with Gym in Northeast Missouri
- Hotels with Hot Tubs in Northeast Missouri
- Hotels with Indoor Pools in Northeast Missouri
- Hotels with Laundry Service in Northeast Missouri
- Hotels with Parking in Northeast Missouri
- Hotels with Parking in Northeast Missouri
- Hotels with Restaurant in Northeast Missouri
- Hotels with Room Service in Northeast Missouri
- Hotels with Swimming Pool in Northeast Missouri
- Hotels with Views in Northeast Missouri
- Hotels with Wifi in Northeast Missouri
- Hotels with a Bar in Northeast Missouri
- Hotels with smoking rooms in Northeast Missouri
- Luxury Hotels in Northeast Missouri
- Pet-Friendly Hotels in Northeast Missouri
- Romantic Hotels in Northeast Missouri
- Shopping Hotels in Northeast Missouri
- Spa Hotels in Northeast Missouri
- Sports Hotels in Northeast Missouri
- Wedding Hotels in Northeast Missouri
More accommodation types in Northeast Missouri
- Apartments in Northeast Missouri
- Holiday Homes in Northeast Missouri
- Motels in Northeast Missouri
- Cottages in Northeast Missouri
- B&B in Northeast Missouri
- Aparthotels in Northeast Missouri
- Guest Houses in Northeast Missouri
- Inns in Northeast Missouri
- Condo Rentals in Northeast Missouri
- Hostels in Northeast Missouri
- Lodges in Northeast Missouri
Explore more hotels
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hilton St. Louis at the Ballpark
- Renaissance St. Louis Airport Hotel
- Wingate by Wyndham St. Louis/Fenton Route 66
- Forest Park Hotel by MDR
- AC Hotel St. Louis Clayton
- Pear Tree Inn St. Louis Airport
- Drury Inn & Suites St. Louis Union Station
- DoubleTree by Hilton St. Louis Airport
- Ameristar Casino Resort and Spa
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Comfort Inn & Suites
- Marriott St. Louis Grand
- Drury Plaza Hotel St. Louis St. Charles
- Holiday Inn St. Louis West Six Flags by IHG
- Baymont by Wyndham Hannibal
- Best Western On The River
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