Compare and book 5 Star hotels in Historic Route 66, United States of America
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Top Historic Route 66 5 Star Hotels

Trump International Hotel & Tower Chicago
Trump International Hotel & Tower Chicago

The Peninsula Chicago
The Peninsula Chicago

The Langham, Chicago
The Langham, Chicago

Four Seasons Hotel Chicago
Four Seasons Hotel Chicago

Nobu Hotel Chicago
Nobu Hotel Chicago

Waldorf Astoria Chicago
Waldorf Astoria Chicago

La Posada de Santa Fe, A Tribute Portfolio Resort & Spa
La Posada de Santa Fe, A Tribute Portfolio Resort & Spa

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
Explore similar 4-star hotels

InterContinental Chicago Magnificent Mile by IHG
Learn more about Historic Route 66
Venture to sights like National Route 66 Museum and Skelly Field at H.A. Chapman Stadium as you discover Historic Route 66.

Top Historic Route 66 Hotel Reviews
Find out more about Historic Route 66
Find out more about Historic Route 66
Stay in Luxury: 5 Star Hotels in Historic Route 66
There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Historic Route 66 trip. You'll join the multitudes of holidaymakers who have made Historic Route 66 so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Historic Route 66 and indulge in the finer things in life for a while.
5-Star Hotels in Historic Route 66
You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Historic Route 66 are waiting for you to relax after an exciting day.
Make Your Escape
The results are in, and Historic Route 66 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Historic Route 66! Choose one of our Historic Route 66 5-star hotels today and soothe yourself in luxe surroundings at your convenience.
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Hotels in Historic Route 66 by Star Rating
Accommodation near Historic Route 66 attractions
- Hotels near Route 66 Raceway
- Hotels near Springfield Expo Center
- Hotels near National Route 66 Museum
- Hotels near Chicago Board of Trade Building
- Hotels near Midewin National Tallgrass Prairie
- Hotels near Atlanta Museum
- Hotels near Cherokee Casino
- Hotels near KiMo Theater
- Hotels near Hammons Tower
- Hotels near Afton Station
- Hotels near Henry's Rabbit Ranch
More accommodation types in Historic Route 66
- Motels in Historic Route 66
- Cottages in Historic Route 66
- Aparthotels in Historic Route 66
- B&B in Historic Route 66
- Resorts in Historic Route 66
- Guest Houses in Historic Route 66
- Apartments in Historic Route 66
- Cabin Rentals in Historic Route 66
- Hostels in Historic Route 66
- Inns in Historic Route 66
- Holiday Homes in Historic Route 66
- Caravan Parks in Historic Route 66
- Farmstay in Historic Route 66
Explore more hotels
- Hotel Felix River North/Magnificent Mile
- Hilton Garden Inn Chicago Downtown/Magnificent Mile
- The Royal Sonesta Chicago Downtown
- Swissotel - Chicago
- Palmer House a Hilton Hotel
- Holiday Inn Chicago Dwtn - The Mart by IHG
- The Allegro Royal Sonesta Hotel Chicago Loop
- River Hotel
- Harrah's Laughlin Beach Resort & Casino
- The Wade
- Radisson Blu Aqua Hotel Chicago
- Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical
- Travelodge by Wyndham Downtown Chicago
- Embassy Suites by Hilton Chicago Downtown Magnificent Mile
- LondonHouse Chicago, Curio Collection by Hilton
- L7 Chicago by LOTTE
- Hilton Chicago
- Hyatt Regency St. Louis at The Arch
- DoubleTree by Hilton Chicago - Magnificent Mile
- Sable at Navy Pier Chicago, Curio Collection by Hilton
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