Compare and book 4 Star hotels in Key Largo, Florida

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
5 Nov - 6 Nov
Tomorrow
6 Nov - 7 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Key Largo 4-star hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,561 reviews)
"Beautiful property, great room, perfect location. Staff were amazing and very nice clean property! Restaurant was excellent"
Canada
William Dean
The price is ₹20,749
₹27,133 total
includes taxes & fees
29 Nov - 30 Nov
Reefhouse Resort & Marina
A beach with lounge chairs and a pier extending into the water.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.8 out of 10, Excellent, (1,197 reviews)
"Very relaxing the beach was nice and pretty from that side of the property clean rooms staff was nice and helpful they made the stay enjoyable"
United States
Damion
The price is ₹24,937
₹33,278 total
includes taxes & fees
15 Nov - 16 Nov
Baker's Cay Resort Key Largo, Curio Collection by Hilton
An aerial view of a resort with a large pool, palm trees, and a beach.

3. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,001 reviews)
"Everything was amazing!!! Beautiful hotel and great location."
United States
Jorge
The price is ₹24,918
₹33,256 total
includes taxes & fees
29 Nov - 30 Nov
Playa Largo Resort & Spa, Autograph Collection
A beach with palm trees, lounge chairs, and a thatched-roof structure.

4. Condo in the Keys

Condo in the Keys
4.0 star property
Tavernier
8.2 out of 10, Very good, (17 reviews)
"Love the location "
United States
Angela
Condo in the Keys
A beachside patio with outdoor seating, palm trees, and a view of the marina.

5. Key Largo Condo - Community Pool, Marina & Beach!

Key Largo Condo - Community Pool, Marina & Beach!
4.0 star property
Key Largo
Key Largo Condo - Community Pool, Marina & Beach!
Balcony

6. The Sanctuary Islet by Florida Keys Luxury Rentals

The Sanctuary Islet by Florida Keys Luxury Rentals
4.0 star property
Key Largo
The Sanctuary Islet by Florida Keys Luxury Rentals
Dining

7. Lime Key by Florida Keys Luxury Rentals

Lime Key by Florida Keys Luxury Rentals
4.0 star property
Buccaneer Point
Lime Key by Florida Keys Luxury Rentals
Pool

8. Coral Palm's Estate by Florida Keys Luxury Rentals

Coral Palm's Estate by Florida Keys Luxury Rentals
4.0 star property
Key Largo
Coral Palm's Estate by Florida Keys Luxury Rentals
Pool

9. Cukoos Nest by Florida Keys Luxury Rentals

Cukoos Nest by Florida Keys Luxury Rentals
4.0 star property
Winston Waterways
Cukoos Nest by Florida Keys Luxury Rentals
Exterior

10. Bay Beach by Florida Keys Luxury Rentals

Bay Beach by Florida Keys Luxury Rentals
4.0 star property
Key Largo
Bay Beach by Florida Keys Luxury Rentals

Top Key Largo Hotel Reviews

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
Reefhouse Resort & Marina

Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo

10/10 Excellent

Great hotel in Key Largo very close to John Pennekamp state park. Good pool and beach area. Would stay again of in the area.
United Kingdom
Cheryl
Reviewed August 2, 2026
Reefhouse Resort & Marina

Find out more about Key Largo

Take Your Pick of 4 Star Hotels in Key Largo

The get-go of any holiday starts with choosing a great spot. Key Largo has been a popular destination with guests because it offers so much to do and see. But, "location, location, location" applies to more than just what city where your plane lands. Now that you have a feel for the town, it's time you to get to know your new digs.

Accommodations as Picturesque as Key Largo

Search Expedia.com.sg for the right 4 Star Key Largo Hotel to suit your fancy. Plenty of these people wrote tips to help you select the accommodation that is the right fit for your holiday.You'll be more than glad to get back to your resort every night. Key Largo has dozens of good options in the 4-star hotel range that create the ideal getaway.

A stay at one of these lodgings ensure that whether you are just relaxing after a day of checking out Key Largo or you are ready to lie down for the night, you'll be as comfortable as possible. You won't go without a thing during your stay at one of these accommodations. Visitors have consistently given them high marks for their attentive service. It's no surprise that loads of guests recommend it.

Reserve a 4-Star Hotel in Key Largo Today!

Your trip to Key Largo should be one that you'll reminisce over for years to come, and booking a 4-star hotel will help create memories that are incredible. Make sure to make a reservation soon. With so few hotels, and plenty of people desiring to vacation in Key Largo, you may miss out on your perfect hotel.

Frequently Asked Questions

What are the best 4-star hotels in Key Largo?

If you're seeking high-quality comfort and loads of amenities on your Key Largo retreat, check in to Playa Largo Resort & Spa, Autograph Collection. This sought-after 4-star hotel comes with a tennis court and massage services. Baker's Cay Resort Key Largo, Curio Collection by Hilton also gets stellar reviews from Expedia travellers. Limousine services and beauty services are among its conveniences.

How much does it cost to stay in a 4-star hotel in Key Largo?

To book a 4-star hotel in Key Largo that's within your budget, make use of Expedia's filter tool. Take a look at what's available during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the most economical stay first.

  • Search for the lowest price from ₹14,645

What's the difference between 5-star and 4-star hotels in Key Largo?

Treat yourself to refined living during your Key Largo holiday by choosing a 4-star hotel. As well as featuring upscale accommodation, these properties are typically packed with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and unforgettable one. Round-the-clock concierge assistance, elegant décor and world-class dining are just the start of the exclusive conveniences and services you'll likely be able to enjoy.

Does Key Largo have any 4-star all-inclusive resorts?

Use our handy filters to find all-inclusive Key Largo retreats where your accommodation, meals, entertainment and lots of other things are included in the one price. No available options? You can also chill out in stylish surroundings at other superb 4-star stays in this destination. Baker's Cay Resort Key Largo, Curio Collection by Hilton and Playa Largo Resort & Spa, Autograph Collection are two top picks.

Are there any 4-star casino hotels in Key Largo?

Use our filter tool to narrow down your Key Largo search by amenities, star rating and more. Whether you're after the complete casino resort experience or simply want to give your luck a try while letting your hair down in 4-star style, you're sure to find a stay that strikes the ideal balance between relaxation and entertainment.

What are the top 4-star hotels in downtown Key Largo?

Explore the attractions effortlessly when you stay at Playa Largo Resort & Spa, Autograph Collection. Only 3 kilometres southwest from the heart of downtown Key Largo, this 4-star hotel places you in the ideal spot to see the most of this bustling city with the added convenience of a swimming pool and a nearby waterfront.