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Most Popular Hotels in Santee
- Rodeway Inn Santee I-95
- Wyndham Vacation Resorts Lake Marion
- Days Inn by Wyndham St George
- Country Inn & Suites by Radisson, Orangeburg, SC
- SpringHill Suites by Marriott Orangeburg
- Holiday Inn Express & Suites Orangeburg
- Baymont by Wyndham Manning
- Baymont by Wyndham Orangeburg North
- Comfort Inn & Suites
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