Sikeston, Missouri, is a delightful destination that offers a range of attractions for all types of travelers. The downtown area is filled with charming cafes, family-friendly dining options, and unique shopping experiences. The city center is conveniently located close to various hotels, making it an ideal base for exploring Sikeston and its surrounding areas. Visitors can enjoy the friendly atmosphere and warm hospitality of the local people while embarking on exciting excursions to the nearby river, university, and museums. Sikeston truly captures the essence of a quintessential American town with its rich history and vibrant culture.

Sikeston Hotels from ₹6,076
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Sikeston
Apartment
Check prices for these dates
Our top choices for Sikeston hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,008 reviews)
The price is ₹10,623
₹12,214 total
includes taxes & fees
22 Jun - 23 Jun

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
The price is ₹10,528
₹11,877 total
includes taxes & fees
21 Jun - 22 Jun

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
The price is ₹10,527
₹11,877 total
includes taxes & fees
14 Jun - 15 Jun

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (574 reviews)
The price is ₹10,203
₹11,552 total
includes taxes & fees
21 Jun - 22 Jun

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,010 reviews)
The price is ₹10,049
₹11,336 total
includes taxes & fees
14 Jun - 15 Jun

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (515 reviews)
The price is ₹12,835
₹14,544 total
includes taxes & fees
1 Jul - 2 Jul

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,009 reviews)
The price is ₹7,369
₹8,313 total
includes taxes & fees
23 Jun - 24 Jun

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (84 reviews)
The price is ₹10,528
₹11,921 total
includes taxes & fees
25 Jun - 26 Jun

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (593 reviews)
The price is ₹11,270
₹12,714 total
includes taxes & fees
10 Jun - 11 Jun

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (779 reviews)
The price is ₹8,868
₹9,597 total
includes taxes & fees
10 Jun - 11 Jun

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,016 reviews)
The price is ₹8,709
₹9,207 total
includes taxes & fees
24 Jun - 25 Jun

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (467 reviews)
The price is ₹10,815
₹12,246 total
includes taxes & fees
28 Jun - 29 Jun

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,007 reviews)
The price is ₹8,728
₹9,948 total
includes taxes & fees
14 Jun - 15 Jun

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (822 reviews)
The price is ₹10,439
₹11,777 total
includes taxes & fees
16 Jun - 17 Jun

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (133 reviews)
The price is ₹8,869
₹10,094 total
includes taxes & fees
17 Jun - 18 Jun

Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.2 out of 10, Very good, (769 reviews)
The price is ₹8,911
₹9,644 total
includes taxes & fees
14 Jun - 15 Jun

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (414 reviews)
The price is ₹7,178
₹7,966 total
includes taxes & fees
10 Jun - 11 Jun

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (196 reviews)
The price is ₹9,820
₹11,078 total
includes taxes & fees
23 Jun - 24 Jun

Rockwood Inn
Rockwood InnCape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
The price is ₹13,233
₹14,929 total
includes taxes & fees
14 Jun - 15 Jun

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (18 reviews)
The price is ₹12,155
₹13,763 total
includes taxes & fees
25 Jun - 26 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Sikeston attractions
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

Top Sikeston Hotel Reviews

Best Western Plus Sikeston I-55
10/10 Excellent
More cheap stays in Sikeston

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
The price is ₹6,547 per night from 17 Jun to 18 Jun
₹6,547
₹7,462 total
17 Jun - 18 Jun
includes taxes & fees
6.8/10 (642 reviews)
Hotels in Sikeston with star rating

3 Star Hotels
17 properties
Find out more about Sikeston
Hidden gem of Southern charm in Sikeston, Missouri
Find your hotel in Sikeston
Experience the top activities and must-see sights in Sikeston
How to find great deals and cheap hotels in Sikeston
Discover the flavours of Sikeston
Best time to go to Sikeston
The Sikeston info point: What you need to know
Category | Details |
|---|---|
| Location | Sikeston, Missouri, United States |
| Population | Approximately 16,000 |
| Climate | Humid subtropical |
| Best time to visit | Spring and fall |
| Must-see attractions | Mississippi River, Lambert's Cafe, Sikeston Depot Museum |
| Local cuisine | Barbecue, Southern comfort food |
| Popular events | Sikeston Jaycee Bootheel Rodeo, Sikeston Cotton Carnival |
| Nearby cities | Cape Girardeau, Poplar Bluff, Paducah (Kentucky) |
Frequently asked questions
Explore a world of travel with Expedia
- Advance Hotels
- B&B in Benton
- Motels in Bragg City
- Campbell Hotels
- Resorts in Cape Girardeau
- All-Inclusive Hotels in Cape Girardeau
- Cheap Hotels in Cape Girardeau
- Hotels with Breakfast in Cape Girardeau
- Motels in Cape Girardeau
- B&B in Charleston
- Cape Girardeau County Hotels
- Resorts in Greenville
- Hotels Suites in Hayti
- Cheap Hotels in Jackson
- Hotels Suites in Jackson
- Hotels near Southeast Missouri State University












































































